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《Chinese Journal of Ethnomedicine and Ethnopharmacy》 2009-10
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Relationship Between the expression of Plkl Gene and Pathobiological Behaviors of Gastric Carcinoma

ZOU Chonggao1 XIA Heshun2(1.Hospital of workers,HU bei,WU Han,430021;2.Cancer Hospital,HU bei,WU Han,430021)  
Objective :To detect the expression of Plkl gene in gastric carcinoma,and to investigate the significance of Plkl gene expression in progression of gastric carcinoma.Methods : The expressions of Plkl were evaluated by immunohistochemistry in 49 cases of gastric carcinoma and the adjacent normal mucosa.Results : The positive rates of Plkl gene expression were 0 and 83.67% in adjacent normal mucosa and gastric carcinoma,respectively.And significant difference in expression of Plkl was found between gastric carcinomas and the adjacent normal mucosa(P0.01).The expression of Plkl was significantly correlated with tumor clinicopathological stage and lymph node metastasis gastric carcinoma(P0.05).Conclusion : Decreased expressions of Plkl gene were significantly correlated with progression and pathobiological behaviors of the stomach carcinoma.
【CateGory Index】: R735.2
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