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《国家科学评论(英文版)》 2017-04
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Paving the road for biomedicine: genome editing and stem cells in primates

Yuyu Niu;Tianqing Li;Weizhi Ji;Yunnan Key Laboratory of Primate Biomedicine Research; Institute of Primate Translational Medicine, Kunming University of Science and Technology;  
Non-human primates(NHPs) are similar with humans in their anatomy, physiology, genetics and neural functions, and in their cognition, emotions and social behavior. The NHP model has played an important role in the biomedical research, development of vaccines and drugs and new therapies for many diseases.Recent advances in genome editing have generated NHP models for human diseases. Genome editing integrated with derivation of NHP pluripotent stem cells now provides an optimal resource to regenerate medicine.
【Fund】: supported by the National Key Research and Development Program of China(2016YFA0101401);; the National Natural Science Foundation of China(U1302227 and U1602224)
【CateGory Index】: Q789
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