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Effects of MK-677 Compound on Exercise Performance of Mice

SHI Wen-hu1, YU Wen-bing2, GAO Li-li3 (1. Sports Bureau of Jiangsu Province, Nanjing, 210008, Jiangsu, China; 2.Nanjing Institute of Physical Education, Nanjing, 210014, Jiangsu, China; 3.Qingdao Medical College of Qingdao University, Qingdao,266003, Shandong, China)  
The effects of MK-677 compound on long-term endurance trained mice were studied in this paper. The results showed: There were remarkable increases of loading swimming time, hemoglobin (p0.05) and body weight (p0.01) when the mice took MK-677 compound. Simultaneously, The activity of LDH and CK and the concentration of BUN decreased remarkably of mice serum after intensive exercise when the mice took MK-677 compound (p0.01). All above suggest that MK-677 compound is capable of enhancing exercise performance of long-term endurance trained mice.
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