Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Pesticide Science and Administration》 2018-11
Add to Favorite Get Latest Update

Determination of Impurities in Batch Analysis of Pesticide Technical Grades

Cao Lidong;Li Fengmin;Huang Qiliang;Wu Jinlong;Zhang Hongjun;Institute of Plant Protection,Chienese Academy of Agricultural Sciences;Institute for the Control of Agrochemicals,Ministry of Agriculture and Rural Affairs of the People's Republic of China;  
The most challenging work for batch analysis of pesticide technical grade(TG) is the qualitative determination of impurities. Impurities are considered to be the "fingerprints"of pesticide TG and are the important parameters to deduce the synthetic route of pesticide TG. The sources of impurities mainly include starting materials,reaction intermediates,and by-products from side reactions. The side reactions are mainly degradation,isomerization,hydrolysis,oxidation,over substitution,and rearrangement reactions. The general idea for determination of impurities is to deduce the tentative chemical structure based on mass spectrum and synthetic route. Further confirmation of the structure of impurity is conducted through the chromatographic and mass comparison with authentic impurity standard which is obtained by custom synthesis(including preparation from preparative chromatography) or commercial available standard. The structure identification of impurity standard is generally performed by NMR,mass spectrum(including high-resolution mass),IR,and X-ray etc.
【CateGory Index】: TQ450.7
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Xu Weichang,Xu Yanan,Su Jinyan,Chang Bo,Wang Yuan (Shenyang Research Institute of Chemical Industry,Shenyang 110021,China);The Full Analysis for Pesticide[J];农药;2003-10
【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 FAN Zhi-xian,LI Jiao,DING Ning,XU Chuan-jun(College of Chemical Engineering,Qingdao University of Science and Technology,Shandong Qingdao 266042,China);Complete Analysis of Fosetyl-aluminum Technical[J];现代农药;2010-06
2 YANG Xiao-yun,FEI Zhi-ping,XU Han-hong(Key Laboratory of Nature Pesticide and Chemical Biology,Ministry of Education,Laboratory of Insect Toxicology,South China Agricultural University,Guangzhou 510642,China);~(31)P NMR Analysis of Malathion and Primary Organic Phosphorus Impurities in Malathion EC[J];波谱学杂志;2009-02
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Lei Rong , Ma Lijuan. Huai Qiyong Zuo Yumin (Department of Chemistry, Nankai University, Tianjin 300071) (Shijiazhuang Huasheng Biochemical Factory, Shijiazhuang 050000);Identification of Ivermectins by High Performance Liquid Chromatography-Electrospray-Mass Spectrometry-Mass Spectrometry[J];分析化学;2002-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved