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Therapeutic effect of cervus and cucumis polypeptide for injection combination with alendronate on postmenopausal osteoporotic fracture

DI Jun,ZHANG Wei,WANG Yan,et al.The 3rd.Affiliated Hospital of Hebei Medical University,Shijiazhuang050051,China  
Objective To observe the effectiveness of integrated the traditional Chinese and western medicine in treating postmenopausal osteoporotic fracture.Methods126 post-menopausal female were diagnosis osteoporosis by DEXA,and at least one pathological fracture confirmed with X-ray.All cases underwent surgery,cervus and cucumis polypeptide for injection(16mg/d,15d),oral alendronate 10mg/d,4 weeks later changed to 70mg/w,20 weeks;surgery only in control group without medicine therapy.The bone mineral density,fracture healing,pain index were evaluated after 24w treatment.ResultsIn treatment group,bone mineral density [(0.72±0.09)g/cm2 vs(0.62±0.07)g/cm2,P0.01]were significantly increased;limbs shaft fractures in the treatment group the average healing time was(12.4±2.9) weeks;for the control group,(16.4±3.3)weeks.There was significant difference between two groups(P0.01).The pain index was lower in treatment group than control group(P0.01) within 1 week,but there was no significant difference after 1w(P0.05).ConclusionThe integrated traditional Chinese and Western medicines could improve the clinical symptoms of osteoporotic fracture,and increase bone density,promoting healing.
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