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《Chinese Journal of Clinical Rational Drug Use》 2017-02
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Efficacy and safety of escitalopram in the treatment of senile depression

ZHANG Meng-xin;The First Social Welfare Institute of Dandong;  
Objective To explore efficacy and safety of escitalopram in the treatment of senile depression.Methods 81 cases of patients with senile depression were selected as the research object.According to different therapeutic methods,they were divided into the control group(n=40,give paroxetine treatment) and the observation group(n=41,give escitalopram citalopram for treatment).The clinical efficacy,HAMD score and adverse reactions were observed and compared between the 2 groups.Results The total effective rate was 95.1%,which was higher than 80.0% of the control group(P 0.05);After treatment,the HAMD scores of the observation group was significantly lower than the control group patients(P 0.05 or P 0.01);The incidence of adverse reactions of the observation group was 7.3%,and it was lower the 27.5% of the control group(P 0.05).Conclusion For patients with senile depression,escitalopram citalopram can significantly improve the clinical efficacy,reduce the degree of depression,reduce adverse reactions,which is worthy of clinical application.
【CateGory Index】: R749.4
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【References】
Chinese Journal Full-text Database 2 Hits
1 HUANG You-li;WU Xu-dong;CHU Hai-yan;Department of Nursing,The Third People's Hospital in Yuyao;Psychosomatic Obstruction,The Third People's Hospital in Yuyao;Psychosomatic ward,The Third People's Hospital in Yuyao;;Study on the effect of SSRI and SNRI combined with psychological intervention on the executive function in patients with depression untreated[J];中国生化药物杂志;2017-08
2 LIU Li;Department of Psychiatry, PLA 102 Hospital;;Comparative Analysis of Escitalopram and Paroxetine in Treatment of Senile Depression[J];系统医学;2017-15
【Citations】
Chinese Journal Full-text Database 2 Hits
1 YUAN Ping;ZHANG Long-hua;LI Ru-hua;Yancheng Fourth People’s Hospital;;Analysis and comparison of curative effect of escitalopram and paroxetine in the treatment of senile depression patients[J];中国实用医药;2014-27
2 Chen Xiaogang;Zhou Dexiang;Zhang Jing;Wuxi Mental Health Center;;Escitalopram and Mirtazapine in the Treatment of Senile Depression[J];中国健康心理学杂志;2014-04
【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 Chen Yan;Beijing Daxing District Geriatric Hospital;;Comparative Effect of Escitalopram and Paroxetine in Treating Senile Depression[J];中国药业;2017-23
2 YANG Fan;Ward of Geriatrics,Shenyang Mental Health Center;;Effect of paroxetine and escitalopram on clinical efficacy and adverse reactions in elderly patients with depression[J];中国老年保健医学;2017-04
3 WEI Xuhua;Departmet of Psychiatry, the Fourth People's Hospital in Liaocheng;;Clinical Efficacy and Safety Studies of Escitalopram and Paroxetine in Patients With First-episode Depression[J];中国卫生标准管理;2017-14
4 ZHANG Meng-xin;The First Social Welfare Institute of Dandong;;Efficacy and safety of escitalopram in the treatment of senile depression[J];临床合理用药杂志;2017-02
5 WANG Fei;Ganzhou city the third people's hospital of ganzhou in jiangxi province;;Escitalopram Citalopram and Paroxetine Treatment of Senile Depression[J];药品评价;2016-24
6 Hu Yalan;Department of Clinical Psychology,the Fourth People's Hospital of Chengdu;;A Comparative Study of the Efficacy and Safety of Escitalopram and Paroxetine in the Treatment of Senile Depression[J];四川医学;2016-11
【Co-references】
Chinese Journal Full-text Database 4 Hits
1 WEI Xuhua;Departmet of Psychiatry, the Fourth People's Hospital in Liaocheng;;Clinical Efficacy and Safety Studies of Escitalopram and Paroxetine in Patients With First-episode Depression[J];中国卫生标准管理;2017-14
2 ZHANG Meng-xin;The First Social Welfare Institute of Dandong;;Efficacy and safety of escitalopram in the treatment of senile depression[J];临床合理用药杂志;2017-02
3 PENG Min;LI Wen-kun;CHEN Yan-zhen;LIU Yu-hai;WEN Xi-jiao;Department of Obstetrics and Gynecology,Chaozhou Xiangqiao Maternal and Child Health Care Hospital;Department of Psychiatry,Chaozhou Third People's Hospital;;The effect of paroxetine combined with psychological adjuvant therapy on clinical efficacy in the treatment of patients with postpartum depression[J];实用医院临床杂志;2017-01
4 Hu Yalan;Department of Clinical Psychology,the Fourth People's Hospital of Chengdu;;A Comparative Study of the Efficacy and Safety of Escitalopram and Paroxetine in the Treatment of Senile Depression[J];四川医学;2016-11
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 GU Yan,JIANG Tao,GUO Jian-Bing,WANG Gang,YU Zhen-Jian,JIANG Bao-Shun,ZHANG Ben,MA Wen-You Kailuan Mental Health Center Affiliated to North China Coal Medical University,Tangshan 063001,Hebei Province,China;Efficacy and safety of escitalopram in elderly patients with major depression:A randomized and control study[J];中国心理卫生杂志;2010-06
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