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Efficacy and safety of escitalopram in the treatment of senile depression

ZHANG Meng-xin;The First Social Welfare Institute of Dandong;  
Objective To explore efficacy and safety of escitalopram in the treatment of senile depression.Methods 81 cases of patients with senile depression were selected as the research object.According to different therapeutic methods,they were divided into the control group(n=40,give paroxetine treatment) and the observation group(n=41,give escitalopram citalopram for treatment).The clinical efficacy,HAMD score and adverse reactions were observed and compared between the 2 groups.Results The total effective rate was 95.1%,which was higher than 80.0% of the control group(P 0.05);After treatment,the HAMD scores of the observation group was significantly lower than the control group patients(P 0.05 or P 0.01);The incidence of adverse reactions of the observation group was 7.3%,and it was lower the 27.5% of the control group(P 0.05).Conclusion For patients with senile depression,escitalopram citalopram can significantly improve the clinical efficacy,reduce the degree of depression,reduce adverse reactions,which is worthy of clinical application.
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