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《Chinese Journal of Clinical Rational Drug Use》 2017-06
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Clinical effect observation of different hemopurification methods in treating chronic renal failure

LI Zhou-qi;Department of Nephrology,Chengdu People 's Hospital of Tianfu New Area;  
Objective To discuss the clinical effect of different hemopurification methods treated on chronic renal failure. Methods A total of 70 cases of chronic renal failure patients were selected from June 2013 to December 2014 in Chengdu People 's Hospital of Tianfu New Area,which were randomly divided into control group and observation group,35 cases in each group. The control group was treated with hemodialysis,the observation group was treated with hemopurification based on control group,both groups were treated for three months. The cognitive function,life quality score,nutritional status( serum prealbumin,serum albumin,cholesterol,hemoglobin),i PTH and improvement of skin pruritus were compared between the two groups. Results After treatment,the observation group of letters cancellation number in letters cancellation test was more than control group,finished time of continuous caleulation test was shorter than control group( P 0. 05). Before treatment,no statistically significant differences in physical agility,daily limitation,bodily pain,physical condition scores was found between the two groups( P 0. 05); after treatment, the physical agility, daily limitation, bodily pain, physical condition scores of observation group were higher than control group( P 0. 05). The observation group of serum prealbumin,serum albumin,hemoglobin levels were higher than control group,cholesterol level was lower than control group( P 0. 05). Before treatment,no statistically significant difference of i PTH level was found between the two groups( P 0. 05); after treatment,i PTH level of observation group was lower than control group( P 0. 05). The observation group of improvement rate of skin pruritus was higher than control group( P 0. 05). Conclusion Hemopurification combined with hemodialysis have an obviously clinical effect treated on chronic renal failure,it can effectively improve cognitive function,nutritional status,i PTH and improvement of skin pruritus,and enhance the quality of life.
【CateGory Index】: R692.5
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