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《Chinese Journal of Clinical Rational Drug Use》 2017-06
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Clinical effect of fluconazole combined with clotrimazole in treating recurrent candidal vulva

YAN Li-hai;Department of Obstetrics and Gynecology,Maternal and Child Health Hospital of Yongxin County;  
Objective To explore the clinical effect of fluconazole combined with clotrimazole in treating recurrent candidal vulva. Methods A total of 200 cases of recurrent candidal vulva patients were selected from January 2013 to January2015 in Maternal and Child Health Hospital of Yongxin County,which were randomly divided into control group and observation group,100 cases in each group. Control group was given fluconazole,observation group was treated with fluconazole combined with clotrimazole,both groups were treated for 3 months. The clinical effect, recurrence rate and hepatic functions indices( AST,ALT) were compared between the two groups. Results The observation group of clinical effect was better than control group,recurrence rate was lower than control group( P 0. 05). The AST,ALT of observation group were lower than control group( P 0. 05). Conclusion Fluconazole combined with clotrimazole have an exactly clinical effect in treating recurrent candidal vulva,it can lower recurrence rate,improve hepatic functions indices.
【CateGory Index】: R711.3
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