Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Clinical Rational Drug Use》 2017-07
Add to Favorite Get Latest Update

Correlation between the levels of serum Cys C and urinary podocalyxin and early renal injury in patients with diabetes mellitus

ZHANG Han;ZHANG Jinxia;HAO Lijie;Department of Medicine,The People' s Hospital of Handan,Hebei Province;  
Objective To study the level of serum Cys C and urinary podocalyxin in patients with type 2 diabetes melitus( T2DM),and analyze the association between the levels of serum Cys C and urinary podocalyxin and the renal injury.Methods Selected 130 cases patients with type 2 diabetic in medical department of People' s Hospital of Handan as patient group,according to the 24 h urine albumin quantitative( 24 h-UAE) level,130 cases patients were divided into normal albuminuria group( urinary albumin 30 mg /24 h,n = 55),microalbuminuria group( 30 ≤urinary albumin 300 mg /24 h,n = 40),macroalbuminuria group( urinary albumin 300 mg /24 h,n = 35). Health check-up of 50 cases as the control group. Compared the levels of serum Cys C and urinary podocalyxin. Results The levels of serum Cys C and urine PCX were higher than control group,the differences were statistically significant( P 0. 05). The levels of serum Cys C and urine PCX In patients with T2 DM group were statistically significant( P 0. 05). The level of serum Cys C was positively correlated with urine PCX( r = 0. 843,P 0. 05) 。Conclusion The levels of serum Cys C,urine PCX can be used as sensitive indicators for the diagnosis of early diabetic nephropathy in patients with diabetes mellitus,it is of great value to early diagnosis and treatment of diabetic nephropathy.
【CateGory Index】: R587.2;R692.9
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 5 Hits
1 LI Ze-yu;LIU Dong;YUAN Wen-ming;Department of Nephrology,the First Affiliated Hospital of Zhengzhou University;;Risk Factors of Diabetic Nephropathy and Critical Value of Blood Pressure Control[J];中国全科医学;2014-20
2 FU Mei-hua,CHEN Jun,CHEN Qiu.Department of Endocrinology,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;Research Progress of Cystatin C and Diabetic Nephropathy[J];中国全科医学;2013-02
3 CHENG Liang,YU Wei-nan,HONG Bing,et al.The Affiliated Huaian Hospital of Xuzhou Medical College,Huaian 223002,China;Clinical Significance of Urinary Podocyte Marker Protein Podocalyxin in the Assessment of Diabetic Nephropathy Level[J];中国全科医学;2012-21
4 ZOU Qi,ZHENG Xiang-xiong.(Department of Nephrology,Union Clinical Medicine College Affliated to Fujian Medical University,Fuzhou 350001,China);Advance of Podocyte Function in Glomerular[J];医学综述;2011-19
5 Zhang Hong,Guo Huaguo,Yao Zhenguo/Center for Disease Control of Huanggang City,Hubei,Huanggang 438000;Diagnostic Value of Serum Cystatin C and UAER for Early Renal Function Injury in Patients with Essential Hypertension[J];微循环学杂志;2011-01
【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 GONG Lun-bin;XIE Xiang-hong;DU Yu;The Clinical Laboratory,Armed Police Corps Hospital of Sichuan Province;;To investigate the early diagnostic value of serum CYS-C and CRP levels in primary hypertensive renal damage[J];中国实验诊断学;2017-03
2 ZHANG Han;ZHANG Jinxia;HAO Lijie;Department of Medicine,The People' s Hospital of Handan,Hebei Province;;Correlation between the levels of serum Cys C and urinary podocalyxin and early renal injury in patients with diabetes mellitus[J];临床合理用药杂志;2017-07
3 MA Pingping;GUO Zhaoan;LI Wei;Shandong University of Traditionanl Chinese Medicine;;Effect of Lianhuang Turbid Clearance Granules on Vascular Endothelial Growth Factor and Podocalyxin in the Renal Tissue of Spontaneously Hypertensive Rats[J];中国中西医结合肾病杂志;2017-01
4 WANG Dan-ni;YU Rui;Department of Endocrinology, the Fifth People′s Hospital of Dalian;;Effects of triptolide on expressions of PGE2 and NF-κB in renal tissue of diabetic nephropathy rats[J];解剖科学进展;2017-01
5 YANG Chao;Department of Urology,the Affiliated Hospital of Inner Mongolia Medical University;;Clinical observation of alprostadil combined with gliquidone in treatment of elderly diabetic nephropathy[J];现代药物与临床;2016-12
6 WANG Yan;LI Jing;HUANG Ping;HUANG Yuyu;SU Yongming;FU Mingjie;Department of Geriatrics Endocrinology,the First People′s Hospital of Guangzhou City Affiliated to Guangzhou Medical College;Department of Geriatrics Nephrology,the First People′s Hospital of Guangzhou City Affiliated to Guangzhou Medical College;;Study on the correlation between serum selenium level and diabetic nephropathy[J];中国医药导报;2016-36
【Secondary Citations】
Chinese Journal Full-text Database 6 Hits
1 LIU Hui-ping.Shandong Province Weicheng District economic development zone People's Hospital,Shandong 261021,China;The clinical expression of serum cystatin C in patients with early diabetic nephropathy[J];中国实用医药;2012-09
2 LI Xiao-lin(Department of Clinical Laboratory,Metabolic Diseases Hospital,Tianjin Medical University,Tianjin 300070,China);Diagnostic value of serum cystain C mensuration in early renal impairment on diabetic nephropathy[J];天津医科大学学报;2011-04
3 CAI Wen-hui.The People's Hospital of Maoming,Maoming Guangdong 525000,China;Clinical significance of detection of serum Cystatin C in early stage of diabetic nephropathy[J];临床和实验医学杂志;2011-04
4 LI Jian-ying,GUO Jin,HUANG Guo-xiu,et al.Senior Officials Inpatient Wards,Guangxi Peole' s Hospital, Guangxi,Nanning 530021,china;The effects of telmisartan and atorvastatin on UAER and Cys C in older patients with early diabetic nephropathy[J];疑难病杂志;2009-10
5 LI Meng~1,HU Jian~1,FANG Hui-Juan~1,FAN Xin~2,and LI Jia-Yu~3(1.Department of Cardiology,2.Department of Radiotherapy;3.Department of Nephrology.The First Affiliated Hospital,China Medical University,Shenyang 110001,China);The Correlation between Leptin and Microalbuminuria in Hypertensive Patients with Impaired Glucose Tolerance[J];中国动脉硬化杂志;2005-05
6 YI Xiangmin, PENG Jie-ya, CHEN Hui. Guangzhou Red- Cross Hospital, Jinan University, Guangzhou 51000, China;The value of serum cystatin C in the early diagnosis of type 2 diabetic nephropathy[J];国际医药卫生导报;2010-16
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved