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《Chinese Journal of Clinical Rational Drug Use》 2017-07
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Efficacy observation of CT-guided radiofrequency ablation combined with concurrent radiotherapy and chemoradiotherapy in the treatment of advanced non-small cell lung cancer

WU Zhijun;Chengdu North Hospital;  
Objective To analyze the efficacy of CT guided radiofrequency ablation combined with concurrent radiotherapy and chemotherapy in the treatment of advanced non-small cell lung cancer. Methods 75 cases of non-small cell lung cancer patients were randomly divided into observation group and control group. Control group was treated with conventional EP regimen,and radiotherapy was the trial radiotherapy. Observation group received CT guided ablation combined with radiotherapy and chemotherapy. After treatment,the effects,the KPS score at the third month,the survival rate and recurrence and metastasis rate within 3 years,adverse reactions between two groups were compared. Results The effective rate in observation group( 86. 84%) was higher than that of control group( 64. 87%)( P 0. 05). After three months' treatment,the KPS score of observation group was significantly improved,the KPS score in control group decreased,the KPS score of observation group was significantly higher than that of control group( P 0. 05 or P 0. 01). There was no significant difference in survival rate between the two groups in 12 and 24 months( P 0. 05). The 36 months' survival rate of observation group was higher than that of control group. The recurrence rate and metastasis rate of observation group were lower than that of control group( P 0. 05).Conclusion CT guided radiofrequency ablation combined with radiotherapy and chemotherapy in the treatment of non-small cell lung cancer has a significant clinical effect,minimally invasive interventional therapy under the guidance of image can be used as the individual treatment of tumor patients.
【CateGory Index】: R734.2
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【Citations】
Chinese Journal Full-text Database 6 Hits
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【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 WU Zhijun;Chengdu North Hospital;;Efficacy observation of CT-guided radiofrequency ablation combined with concurrent radiotherapy and chemoradiotherapy in the treatment of advanced non-small cell lung cancer[J];临床合理用药杂志;2017-07
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