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《Chinese Journal of Clinical Rational Drug Use》 2017-07
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Clinical efficacy and safety observation of budesonide inhalation therapy in treatment of children with acute infectious laryngitis

YAN Guangxing;LU Wei;GAO Lei;Department of Pediatric,Linzi District People' s Hospital of Zibo City,Shandong Province;  
Objective To observe the clinical efficacy and safety of budesonide( pulmicort) inhalation therapy in treatment of children with acute infectious laryngitis. Methods 96 children with acute infectious laryngitis from March 2015 to October 2016 in hospital were randomly divided into observation group and control group,with 48 cases in each group. On the basis of conventional treatment,observation group was given pulmicort aerosol inhalation; control group was given hydrocortisone sodium succinate to pine vein infusion. Treatment effect,clinical manifestations of disappearance time and adverse reactions between two groups were compared. Results The significant efficiency and total efficiency of observation group were 45. 83%and 83. 33% respectively,and the control group were 31. 25% and 62. 50% respectively. The significant efficiency and total efficiency of observation group were higher than that of control group( P 0. 05). Fever,barking cough,inspiratory wheeze and hoarseness disappeared time were all shorter than control group,the differences were statistically significant( P 0. 05). There was no obvious adverse reaction in two groups. Conclusion Pulmicort inhalation in treatment of children with acute infectious laryngitis can achieve better results,with the effective rate of treatment can be improved,shorter treatment time,relieve pain in children is also easy to be understood and accepted by the families of the children,and has important clinical significance.
【CateGory Index】: R767.11
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 SONG Yongyao;ZHOU Xiong;ZHENG Rong;ZHOU Qiong;Department of Internal Medicine,Shuifu People's Hospital;Daguan Health Hospital;;Efficacy observation of pulmicort respules inhalation in treatment of children with acute infectious laryngitis[J];中国医药科学;2014-06
2 ZHAO Juan.Department of Health Care,The People's Hospital of Sichuan,Chengdu 610072,China,;Analysis of the effect of different methods on acute infectious laryngitis in children[J];中国医药;2013-08
【Co-citations】
Chinese Journal Full-text Database 7 Hits
1 YAN Guangxing;LU Wei;GAO Lei;Department of Pediatric,Linzi District People' s Hospital of Zibo City,Shandong Province;;Clinical efficacy and safety observation of budesonide inhalation therapy in treatment of children with acute infectious laryngitis[J];临床合理用药杂志;2017-07
2 CHEN Xue-cai;Pediatric, Le'an People's Hospital;;The Clinical Effect of Budesonide Inhalation on Acute Infectious Laryngitis in Children[J];药品评价;2016-24
3 LI Huajuan;Department of ENT,The Second People's Hospital of Zhenping County;;Clinical Effect of Pulmicort in the Treatment of Children With Acute Infectious Laryngitis[J];中国继续医学教育;2016-28
4 ;Budesonide inhalation treatment with mixed suspension pediatric clinical effectiveness and safety of acute infectious laryngitis[J];北方药学;2016-09
5 WAN Dehuang;The First Pediatric Department,the People's Hospital of Wuhua County,Guangdong Province;;The clinical curative effect of different hormone aerosol inhalation for children with acute laryngitis complicated with dyspnea[J];中国医药科学;2016-10
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7 FANG Shi-jin;Department of Respiration,Anhui Provincial Children's Hospital;;Clinical efficacy of inhaletion of budesonide and epinephrine on acute infectious laryngitis in children[J];安徽医药;2014-04
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