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《Chinese Journal of Clinical Rational Drug Use》 2017-12
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Clinical effect of alprostadil combined with low molecular weight heparin calcium in treating hyperlipidemic pancreatitis

LI Lan-fu;Department of Gastroenterology,People's Hospital of Yanbian County;  
Objective To study the clinical effect of alprostadil combined with low molecular weight heparin calcium in treating hyperlipidemic pancreatitis. Methods A total of 148 cases of hyperlipidemic pancreatitis patients were selected from May 2012 to October 2016 in People' s Hospital of Yanbian County,which were randomly divided into control group and study group,74 cases in each group. Patients were given conventional basic therapy,control group was treated with alprostadil,study group was treated with low molecular weight heparin calcium on the basis of control group,both groups were treated for 15 days. The clinical effect,pancreatitis symptoms improvement time,serum amylase recovery time and total fasting time,pancreatitis CT scores and TG levels before and after treatment were compared between the two groups. Results The clinical effect of study group was better than control group( P 0. 05). The study group of pancreatitis symptoms improvement time,serum amylase recovery time and total fasting time were shorter than control group( P 0. 05). Before treatment,no statistically significant differences of pancreatitis CT scores or TG levels was found between the two groups( P 0. 05); after treatment,the study group of pancreatitis CT scores and TG levels were lower than control group( P 0. 05). Conclusion Alprostadil combined with low molecular weight heparin calcium have an exactly clnical effect in treating hyperlipidemic pancreatitis patients,it can effectively improve the clinical symptoms and signs of patients,and promote the recovery of pancreatitis.
【CateGory Index】: R576
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