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《Chinese Journal of Clinical Rational Drug Use》 2017-14
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Comparison of the efficacy of aripiprazole and quetiapine in treatment of elderly patients with schizophrenia

SUN Xiang-hong;GUO Yan-hong;Qingdao mental health center of Shandong;  
Objective To compare the efficacy of quetiapine and apelizole in treatment of elderly patients with schizophrenia. Methods Seventy elderly patients with schizophrenia were randomly divided into two groups: the control group and the study group with 35 cases of each. Group A was given quetiapine treatment,group B was treated with aripiprazole; the treatment of 2 groups of patients and the relevant clinical indicators( prolactin,BMI,blood glucose) were observed and compared.Results The total effective rate,in group A was 94. 29%,the control group was 91. 43%. The statistical difference between the two groups is not significant( P 0. 05); There were no significant differences in the BMI index between the two groups before and after treatment( P 0. 05). The levels of prolactin and blood glucose in group A were significantly changed before and after treatment( P 0. 05) indicating that group B is superior to group A in safety. Conclusion In the treatment of elderly schizophrenia,quetiapine and aripiprazole have similar efficacy. But aripiprazole is superior to quetiapine in the perspective of safety.
【CateGory Index】: R749.3
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【Citations】
Chinese Journal Full-text Database 5 Hits
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【Co-citations】
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1 JIAN Wei;RUAN Xi;WANG YU;ZHANG Lang;Department of Geriatrics,The Fourth People's Hospital of Chengdu;Department of Psychiatry,The Fourth People's Hospital of Chengdu;;The effects of quetiapine combined with oryzanol on clinical symptoms,blood glucose and lipid metabolism in elderly schizophrenic patients[J];西部医学;2017-06
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