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《Chinese Journal of Clinical Rational Drug Use》 2017-14
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Clinical analysis of treatment of intrauterine adhesions with estradiol valerate

YU Chun-hao;WU Hong-rui;LIU Qiao-ying;Department of Gynaecology and Obstetrics Qingdao No.9 People's Hospital;  
Objective To observe the clinical effect of using estradiol valerate in the treatment of intrauterine adhesions after hysteroscopy. Methods 69 cases in our hospital after hysteroscopic surgery application of estradiol valerate therapy patients formed the study group,and 69 cases with implementation of hysteroscopic surgery while without application of estradiol valerate in the same period formed control group. The two groups were followed up regularly to analyze the therapeutic effect,endometrial thickness,adverse reaction and conception. Results The effective rate was 94. 2% in the observation group higher than that of 59. 4% in the control group. The average thickness of the endometrium in the observation group was( 9. 7 ± 2. 7)mm,which was thicker than that in the control group( 4. 2 ± 2. 3) mm; There were 37 cases of successful conception greater than that of 19 cases in the control group. The difference between the data groups was statistically significant( P 0. 05 or P 0. 01). The difference of the data between the groups were statistically significant. among 69 patients in study group,there were7 cases of nausea after taking drugs,relatively mild and tolerated,and no serious liver and kidney dysfunction in patients were found. Conclusion The effect of the application of estradiol valerate in the treatment of intrauterine adhesions after hysteroscopic surgery is significant,which is helpful for endometrial recovery and conception with fewer side effects and worthy of clinical promotion.
【CateGory Index】: R713.4
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 MU Xiao-Ling.Department of Gynecology and Obstetrics,the First Hospital Affiliated to Chongqing Medical University,Chongqing 400013,China;Therapeutic effect of estradiol valerate on intrauterine adhesion[J];中国妇幼保健;2010-09
2 TIAN Qin-Jie,WEN Xiu-Yan,CHEN Rong.Department of Obstetrics and Gynecology;Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100730,China;Clinical observation of estradiol valerate for prevention of uterine adhesion after hysteroscopic therapy[J];中国妇幼保健;2006-12
【Co-citations】
Chinese Journal Full-text Database 6 Hits
1 YU Chun-hao;WU Hong-rui;LIU Qiao-ying;Department of Gynaecology and Obstetrics Qingdao No.9 People's Hospital;;Clinical analysis of treatment of intrauterine adhesions with estradiol valerate[J];临床合理用药杂志;2017-14
2 JI Liu;LI Xiao-jun;WU Wen-hui;YAN Li-li;Department of Pharmacy,Dalian Maternal and Child Health Hospital;;Practice and experience of medication consultation service for off-label use of estradiol valerate[J];实用药物与临床;2016-12
3 WANG Xiao-wan;BIAN Ai-ping;ZHAO Qian;JING Zhi-ying;LI Kai-li;SUN Cui-cui;ZHANG Xiu-xiu;Department of Gynecology and Obstetrics,The First Affiliated Hospital of Zhengzhou University;;Efficacy analysis of Interceed in patients with moderate-to-severe intrauterine adhesions after hysteroscopic surgery[J];中国计划生育和妇产科;2016-06
4 Xin QI;Xiao-dong LI;The Second Hospital of Hebei Medical University;;Application and mechanism of estrogen in intrauterine adhesion[J];生殖与避孕;2016-01
5 SUN Gui-ling;Department of Obstetrics and Gynecology,Maternal and Child Care Service Centre of Laixi City in Shandong Province;;Clinical effects observation of estradiol valerate combined with misoprostol for removal of intrauterine device on postmenopausal women[J];中国当代医药;2016-01
6 HE Ming-xian;Department of Endocrinology,General Hospital of Pangang Group;;Observation of Progynova in Perimenopausal Syndrome and Effect on Bone Mineral Density[J];临床误诊误治;2015-09
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