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《Chinese Journal of Clinical Rational Drug Use》 2017-14
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Clinical observation of metronidazole combined with clindamycin in the treatment of bacterial vaginitis

YANG Zhao-jing;The 731 Hospital of China Aerospace Science and Industry Group;  
Objective To investigate the clinical efficacy and safety of metronidazole combined with clindamycin in the treatment of bacterial vaginitis. Methods 186 patients with bacterial vaginitis were randomly divided into control group( n = 93) and observation group( n = 93). In the control group,patients were treated with metronidazole. The observation group was treated with clindamycin on the basis of metronidazole treatment,and the clinical treatment effect and the recurrence of the disease were observed. Results The total effective rate was 96. 8% in the observation group,higher than that of 78. 5%in the control group( P 0. 05). The recurrence rate was 9. 7% in the observation group and lower than that of 32. 3% in the control group( P 0. 05). Conclusion Clinical effect of metronidazole combined with clindamycin treatment of bacterial vaginitis is significant,safe and worthy of clinical application.
【CateGory Index】: R711.31
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