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《Chinese Journal of Clinical Rational Drug Use》 2017-16
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Expressions and significance of p57~(KIP2) in hydatidiform mole

HE Juan;SUN Qi;LU Meiying;Department of Pathological Section,The Fourth Affiliated Hospital of GuangXi Medical University;  
Objective To observe the expression of p57KIP2 protein in complete hydatidiform mole(CHM) and partial hydatidiform mole(PHM),and to explore the role and significance of p57KIP2 protein in the diagnosis and differential diagnosis of CHM and PHM. Methods Immunohistochemical method was used to detect the expression of p57KIP2 protein in 25 cases of CHM and 35 cases of PHM. At the same time,30 cases of placental tissue of edema abortion were selected as control group.Results The expression of p57KIP2 protein in chorionic villous cells and villus stromal cells of CHM was significantly lower than that of PHM and edematous abortion placenta,the difference was statistically significant(P 0. 05). Conclusion Immunohistochemical detection of p57KIP2 protein can be used as an important reference index in differential diagnosis of CHM and PHM.
【CateGory Index】: R737.33
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【Citations】
Chinese Journal Full-text Database 4 Hits
1 Li Xinmin;Gu Yali;Ren Zhimin;Zhang Maona;Qian Jin;Wang Tianqi;Department of Pathology, Women and Infants Hospital of Zhengzhou;;Missed diagnosis and misdiagnosis of hydatidiform mole after artificial abortion[J];中华临床医师杂志(电子版);2015-20
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【Co-citations】
Chinese Journal Full-text Database 8 Hits
1 JING Fu-xiang;YUAN Xue-qin;SHI Yong-can;Affiliated Jinxiang Hospital of Jining Medical College;;Application of Short Tandem Repeat Analysis in Diagnosis of Partial Hydatidiform Mole[J];肿瘤学杂志;2018-01
2 LI Fu-liang;LIU Chun-ying;WANG Yun;WANG Jian;ZHUANG Zhen-juan;Department of Pathology,Anqiu People's Hospital;;The significance of the expression of p57,CD34 and Ki-67 in edematous lesions of placental villi[J];新乡医学院学报;2018-01
3 HE Juan;SUN Qi;LU Meiying;Department of Pathological Section,The Fourth Affiliated Hospital of GuangXi Medical University;;Expressions and significance of p57~(KIP2) in hydatidiform mole[J];临床合理用药杂志;2017-16
4 Zhang Kun;Bai Shi;Department of Pathology,Suqian Municipal Zhongwu Hospital;;Application value of p57,p53 and Ki-67 in diagnosis of hydatidiform mole[J];现代医药卫生;2016-22
5 ZHU Honglan;LI Yi;LIU Guoli;WANG Shijun;ZHANG Xiaohong;LI Xiaoping;Department of Obstetrics and Gynecology, Peking University People's Hospital;;Outcomes of complete hydatidiform mole and a coexistent viable fetus:status in China[J];中国妇产科临床杂志;2015-06
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7 HAN Shu-zhen;WANG Du-juan;ZENG Li-hua;HE Dan;CHEN Xiao-yi;Department of Pathology , Affiliated Houjie Hospital of Donggaun ,Guangdong Medical University;Department of Pathology , Guangdong Medical University;;Diagnostic Value of p57, p53 and p63 Proteins in Distinguishing Hydatidiform Mole from Hydropic Abortion[J];岭南急诊医学杂志;2015-04
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