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《Chinese Journal of Clinical Rational Drug Use》 2017-18
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Diagnostic value analysis of Copeptin,cTnI and the combined detection in the early acute myocardial infarction

DONG Yan;CHEN Meng-fei;CHEN Zhan-long;Ningxia Medical University;  
Objective To investigate the diagnostic value of Copeptin,cTnI and the combined detection in the early acute myocardial infarction(AMI).Methods A total of 132 cases of patients with chest pain for 4 h were admitted from July to December 2015 in Ningxia People's Hospital,which were divided into normal group(n=42) and AMI group(n=90) according to CAG detection.The Copeptin,cTnI were detected and compared between the two groups,and the diagnostic value of Copeptin,cTnI and the combined detection in the early AMI were analysized.Results After chest pain for 4 h,6 h,the AMI group of Copeptin and cTnI levels were higher than normal group(P0.05).The results of CAG as gold standard,the Copeptin combined with cTnI detection of sensitivity was 96.67%,specificity was 80.95%,positive predictive value was 91.58%,negative predictive value was 91.89%,accuracy was 91.67%;the Copeptin detection of sensitivity was 91.11%,specificity was 57.14%,positive predictive value was 82.00%,negative predictive value was 75.00%,accuracy was 80.30%;the cTnI detection of sensitivity was 75.56%,specificity was 71.43%,positive predictive value was 85.00%,negative predictive value was 57.69%,accuracy was 74.24%.Conclusion Chest pain for 4 h of patients,Copeptin combined with cTnI detection is helpful to the rapid screening of AMI patients in Emergency Department,and improve the early diagnosis rate of AMI.
【CateGory Index】: R542.22
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1 DONG Yan;CHEN Meng-fei;CHEN Zhan-long;Ningxia Medical University;;Diagnostic value analysis of Copeptin,cTnI and the combined detection in the early acute myocardial infarction[J];临床合理用药杂志;2017-18
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