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《Chinese Journal of Clinical Rational Drug Use》 2017-18
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Diagnostic value analysis of Copeptin,cTnI and the combined detection in the early acute myocardial infarction

DONG Yan;CHEN Meng-fei;CHEN Zhan-long;Ningxia Medical University;  
Objective To investigate the diagnostic value of Copeptin,cTnI and the combined detection in the early acute myocardial infarction(AMI).Methods A total of 132 cases of patients with chest pain for 4 h were admitted from July to December 2015 in Ningxia People's Hospital,which were divided into normal group(n=42) and AMI group(n=90) according to CAG detection.The Copeptin,cTnI were detected and compared between the two groups,and the diagnostic value of Copeptin,cTnI and the combined detection in the early AMI were analysized.Results After chest pain for 4 h,6 h,the AMI group of Copeptin and cTnI levels were higher than normal group(P0.05).The results of CAG as gold standard,the Copeptin combined with cTnI detection of sensitivity was 96.67%,specificity was 80.95%,positive predictive value was 91.58%,negative predictive value was 91.89%,accuracy was 91.67%;the Copeptin detection of sensitivity was 91.11%,specificity was 57.14%,positive predictive value was 82.00%,negative predictive value was 75.00%,accuracy was 80.30%;the cTnI detection of sensitivity was 75.56%,specificity was 71.43%,positive predictive value was 85.00%,negative predictive value was 57.69%,accuracy was 74.24%.Conclusion Chest pain for 4 h of patients,Copeptin combined with cTnI detection is helpful to the rapid screening of AMI patients in Emergency Department,and improve the early diagnosis rate of AMI.
【CateGory Index】: R542.22
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【Citations】
Chinese Journal Full-text Database 4 Hits
1 QIAN Zhou-nan;ZHANG Hao;REN Guo-qing;Department of Emergency,Affiliated Hospital of Jiangsu University;;Value of copeptin and cTnI in early diagnosis of acute myocardial infarction[J];中国实验诊断学;2014-11
2 PENG Ji-ren;GE Xuan;Department of Cardiology,People's Hospital of Dongyang;;Diagnostic Value of Combined Examination of Copeptin and High Sensitivity Cardiac Troponin T in Patients at Early Stage of Acute Myocardial Infarction[J];中国循环杂志;2014-10
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4 YAN Xiaoju1 LIU Song1 HUANG Yuxiao2 (1Cardiology Department of Affiliated Hospital of Qingdao University Medical College,Qingdao 266003,China;2Interventional Radiology Department,Qindao Haici Medical Company);Relationship of plasma Copeptin and short-term prognosis of patients with acute myocardial infarction[J];临床心血管病杂志;2011-09
【Co-citations】
Chinese Journal Full-text Database 9 Hits
1 DONG Yan;CHEN Meng-fei;CHEN Zhan-long;Ningxia Medical University;;Diagnostic value analysis of Copeptin,cTnI and the combined detection in the early acute myocardial infarction[J];临床合理用药杂志;2017-18
2 XU Feng;WANG Huailong;ZHAO Wei;CHENG Jie;Dongguan Taixin Hospital;;Value of hs-CTnT in Diagnosis of Acute Myocardial Infarction[J];现代医院;2017-05
3 ;Emergency link quality control's influence in CK-MB,hs-cTnI and BNP in patients with AMI[J];临床急诊杂志;2017-05
4 LI Xiu-qi;WANG Han;YU Wen;HAN Jing;Department of Cardiology,Yangzte River Shipping General Hospital;;Value of high-sensitive cardiac troponin T to early diagnosis of acute non-ST-segment elevation myocardial infarction[J];中国循证心血管医学杂志;2017-04
5 YING Kai-qiang;ZHOU Lin;XU Cong-rong;Teaching and Research Section of Clinical Biochemistry,School of Laboratory Medicine,Changsha Medical College;Department of Clinical Laboratory,Subsidiary The Second People's Hospital,Fujian University of Traditional Chinese Medicine;;Value of the combination of troponin and copeptin in the early diagnosis of acute myocardial infarction:A meta-analysis[J];临床检验杂志;2017-03
6 WANG Xiu-quan;ZHAO Xiao-jun;LAN Hui;Department of Clinical Laboratory, Zigong Third People's Hospital;;Effect of Different Types of Samples in the Rapid Bedside Test of cTnI on the Test Results[J];中国卫生产业;2017-09
7 BAI Yantao;SHI Quanbao;LI Yan;Dept. of Cardiology,Nanyang Second People's Hospital;Dept. of Infection,Nanyang Central Hospital;;Clinical Study of Fructose Sodium Diphosphate in the Treatment of Acute Myocardial Infarction[J];中国药房;2017-08
8 YE Ji-zhang;Huizhou Central People's Hospital;;Senile Acute Myocardial Infarction Combined with Reteplase Tirofiban Treatment Effect on the Onset time and the Related Index of Blood and Microcirculation[J];血栓与止血学;2017-01
9 TAN Hanwen;No.3 Medicine Department of People Hospital of Zijin County;;Significance of plasma copeptin level in patients with STEAMI in the assessment of MACE at the time of hospitalization[J];包头医学院学报;2017-02
【Secondary Citations】
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1 ZHAO Yu-qing;YUAN Gui-li;ZhANG Jin-shun;YAN Qing-ye;LI Fang-jiang;WANG Xiao-yun;YANG Miao;Department of Cardiology,The First Affiliated Hospital of Hebei North University;;Prognostic Value Assessment of Copeptin and NT-proBNP in Patients With Chronic Heart Failure[J];中国循环杂志;2014-04
2 SUN Qing-wen;CHEN Huan-qin;WANG Quan-zhen;Department of Health Care, Shandong University Qilu Hospital;;The Correlation Between Serum Levels of Copeptin and N-Terminal Pro-Brain Natriuretic Peptide in Patients With Heart Failure[J];中国循环杂志;2013-07
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