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《Chinese Journal of Clinical Rational Drug Use》 2017-35
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Therapeutic value of irbesartan combined with amlodipine in elderly hypertension with diabetes mellitus

ZENG Xiao-hua;LONG Ying;People's Hospital of Wanzai;  
Objective To explore the clinical effect of using irbesartan combined with amlodipine in the treatment of elderly patients with hypertension and diabetes mellitus.Methods 90 cases of elderly patients received by our hospital with hypertension with diabetes were selected as a study sample,and randomly divided into the control group and observation group,with each group of 45 cases.The control group was treated with irbesartan and the observation group was treated with irbesartan combined with amlodipine.The clinical treatment results were observed and compared.The changes of fasting blood glucose and fasting insulin were observed before and after treatment.Results The total effective rate of observation group was 95.56%,higher than 82.22% of the control group(P0.05).After treatment,the fasting blood glucose and fasting insulin levels in both groups were lower than those before treatment,and the improvement in the observation group was better than that in the control group(P0.05).After treatment,systolic blood pressure and diastolic blood pressure were lower in both groups than those before treatment,and the decrease in the observation group was greater than that in the control group(P0.05).Conclusions The application of using irbesartan and amlodipine in the treatment of the elderly patients with hypertension and diabetes mellitus has a positive effect,which effectively improved the clinical treatment efficiency and lowers patients' blood glucose and blood pressure.
【CateGory Index】: R544.1;R587.1
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