Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Periodical of Ocean University of China》 2015-01
Add to Favorite Get Latest Update

Study of Inhibitory Capability of the Water Phase Extracts from Uiva pertusa Against Xanthine Oxidase

YAN Cui-Wei;CHANG Bao;LI Jing;TIAN You-Hao;College of Marine Life Science,Ocean University of China;  
The water phase extracts of Uiva Pertusa was prepared by low temperature drying,ethanol digestion,vacuum concentration,ethyl acetate and diethyl ether extraction.The inhibitory capability of the extracts of Uiva Pertusaagainst xanthine oxidase was studied with K2HPO4-KH2PO4 as buffer solution(pH= 7.5)and at 25℃.The results showed that water phase extracts of Uiva Pertusa could inhibit the activity of Xanthine Oxidase obviously.The concentration corresponding to 50%inhibitory rate(IC50)was 0.58mg/mL.The inhibition kinetics analyzed by Lineweaver(Burk plotting demonstrated that the water phase extracts was uncompetitive reversible inhibitor to xanthine oxidase,with an inhibition constant(kIS)of 0.40mg/mL.The study of combined inhibitory effects showed that it was weak synergy between water phase extracts and allopurinol.
【Fund】: 青岛市科技计划基础研究项目(11-2-4-1-(9)-gch);; 国家海洋局海洋活性物质与现代分析技术重点实验室开放基金项目(MBSMAT-2012-05)资助
【CateGory Index】: Q55
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 10 Hits
1 Ye Yong1,Luo Yueting2,Xu Xingcang2 1.Pharmaceutical Engineering Department of Chemistry and Chemical Engineering College,South China University of Technology,Guangzhou(510640);2.Guangdong Cangheng Agriculture Development Co.Ltd;Experimental Study on Compound Recipe of Traditional Chinese Medicines for Gout[J];Journal of Zhejiang Chinese Medical University;2012-06
2 JIANG Tong-wei1,XU Jian2,WANG Xiao-ming3,CHEN Xue-song,QIU Zhi-dong1(1.School of Pharmacy,Changchun University of Chinese Medicine,Changchun 130117,China;2.Jilin Province Xiuzheng Pharmaceutical Group,Changchun 130012,China;3.Department of Cardiology,First Hosptal,Jilin University,Changchun 130021,China);Screening of active ingredient of Stigmata maydis inhibitrg xanthine oxidase and its effect[J];Journal of Jilin University(Medicine Edition);2011-03
3 SHANG Yan-jun~(1),GUO Yue-wei~(2),HUANG Cai-guo~(1*),JIA Rui~(2),XU Qiang-zhi~(1),WEI Shan-jian~(1),JIAO Bin-hua~(1),ZHANG Jian-rong~(3) (1.Department of Biochemistry and Molecular Biology,College of Basic Medical Sciences,Second Military Medical University,Shanghai 200433,China;2.Shanghai Institute of Materia Medica,Shanghai 201203;3.Department of Clinical Laboratory,Changhai Hospital,Second Military Medical University,Shanghai 200433);Inhibition of xathine oxidase by renierol extracted from South China Sea sponge[J];Academic Journal of Second Military Medical University;2006-01
4 KANG Kai 1,WANG Changyun1,WANG Bingui2,LI Guoqiang1(1.Institute of Marine Drugs,Ocean University of China;Key Laboratory of MarineDrugs,Ministry of Education,Qingdao 266003,China;2.Laboratory of Experimental Marine Biology,Institute of Oceanology,Chinese Academy of Sciences,Qingdao,266071,China);RECENT PROGRESS ON THE CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITIES OF MACROALGAE Ulva pertusa[J];Transactions of Oceanology and Limnology;2007-03
5 Su Xiurong, Li Taiwu, Chang Shaojie (Institute of Food Biochemistry, Liaoning Normal University, Dalian 116029);A STUDY ON NUTRITION OF ULVA PERTUSA KJELLM[J];Chinese Journal of Marine Drugs;1997-01
6 Wang Yan-mei, Li Zhi-en, Niu Xi-zhen, et al. (Institute of Oceanology , Chinese Academy of Sciences , 266071, China);A preliminary study on antilipemic activity of polysaccharides from Ulva pertusa in mice[J];Chinese Journal of Marine Drugs;2003-02
7 LI Bo1,HUANG Ming-ju2,LI Yan-lan2,ZENG Guang-yao2,TAN Jian-bing2,ZHOU Ying-jun2 (1.Hunan food and drug administration,Changsha 410013,China;2.School of pharmaceutical science,Central South University,Changsha 410013,China);Antioxidant constituents of Sarcandra glabra(Thunb.)Nakai[J];Journal of Shenyang Pharmaceutical University;2009-11
8 ZHAO Ying,ZHANG Qi-hong,FENG Ming-sheng,YAO Qi-zheng(Department of Medicinal Chemistry,China Pharmaceutical University,Nanjing 210009,China);Advances in the Research of Xanthine Oxidase Inhibitors for Lowering Urate[J];Progress in Pharmaceutical Sciences;2009-02
9 LI Ying,CHEN Jun ,LI Ping Key Laboratory of Modern Chinese Medicines(Ministry of Education),China Pharmaceutical University,Nanjing 210009,China;Inhibitory activity of the flavonoids and phenolic acids from Jinyinhua on the xanthine oxidase[J];Journal of China Pharmaceutical University;2011-05
10 LIANG Yong1,ZHAO Yong2,CHEN Bo3,YANG Jing-yu3,WANG Fang-yang3,WANG Shao-jie3 (1.Liaoning Haisco Pharmaceutical Co.,Ltd.,Xingcheng 125107,China; 2.School of Chemical Engineering,Shenyang University of Chemical Technology,Shenyang 110142,China; 3.School of Pharmaceutical Engineering,Shenyang Pharmaceutical University,Shenyang 110016,China);Synthesis and xanthine oxidase inhibitory activites of 2-phenyl-5-pyridyl-1,3,4-oxadiazole derivatives[J];Chinese Journal of Medicinal Chemistry;2012-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 JIANG Tong-wei1,XU Jian2,WANG Xiao-ming3,CHEN Xue-song,QIU Zhi-dong1(1.School of Pharmacy,Changchun University of Chinese Medicine,Changchun 130117,China;2.Jilin Province Xiuzheng Pharmaceutical Group,Changchun 130012,China;3.Department of Cardiology,First Hosptal,Jilin University,Changchun 130021,China);Screening of active ingredient of Stigmata maydis inhibitrg xanthine oxidase and its effect[J];Journal of Jilin University(Medicine Edition);2011-03
2 TAO Ping\+1,HE Feng-wei\+2 (1.Dept.of Aquaculture,Dalian Fisheries College,116023,China;2.Benxi College of Metallurgy,Benxi,Liaonin~g,117022,China);An Analysis of Inorganic Natrition Elements from Thirteen Kinds of Quick-growth Seaweeds along Dalian Coastline[J];Journal of Benxi College of Metallurgy;2001-03
3 SU Yan-ming,CAI Xue-xin,SUN Jian, ZHOU Wei (School of Life Science and Technology,Dalian Fisheries University,Dalian 116023,China);Effects of several kinds of feedstuff on growth and digestibility of juvenile sea urchin Strongylocentrotus intermedius[J];Journal of Dalian Fisheries University;2008-03
4 WANG Shan,LIU Yu,ZHANG Song(Environmental Information Institute,Dalian Maritime University,Dalian 116023,China);Effects of petroleum hydrocarbon on growth and photosynthesis in sea weed macroalga Ulva pertusa[J];Journal of Dalian Ocean University;2011-05
5 QI Xin,WANG Chang-lu,LI Feng-juan,CHEN Mian-hua,WANG Yu-rong,LI Zhuan,LI Ya-di(College of Food Engineering and Biotechnology,Tianjin μniversity of Science and Technology,Tianjin 300457);Inhibitory Effects of the Extracts of Some Common Vegetables on Xanthine Oxidase[J];Modern Food Science and Technology;2011-05
6 Kazeem MI;Akanji MA;Hafizur Rahman M;Choudhary MI;Department of Biochemistry,University of llorin;Department of Biochemistry,Lagos State University;Dr.Panjwani Center for Molecular Medicine and Drug Research,International Center for Chemical and Biological Sciences,University of Karachi;;Antiglycation,antioxidant and toxicological potential of polyphenol extracts of alligator pepper,ginger and nutmeg from Nigeria[J];亚太热带生物医学杂志(英文版);2012-09
7 LIU You-hao;ZHAO Li-chao;LU Jia-xin;ZHONG Yi-lin;CHENG Hong-zhang;CAO Yong;College of Food Science, South China Agricultural University;;Inhibition effects on xanthine oxidase and kinetics research of extracts from eucalyptus leaves[J];Guangdong Agricultural Sciences;2014-14
8 ZHANG Ya-qin;Benxi Chemical Industrial School;;Analysis of Inorganic Nutritive Elements from Quick-growth Economic Seaweeds along Dandong Coastland[J];Journal of Liaoning Institute of Science and Technology;2014-02
9 CHENG Hong,SONG Enfeng,REN Kaiming Dept.of Traditional Chinese Medicine,Renmin Hospital of Wuhan University,Wuhan 430060,China;Clinic Effect of Benzbromarone Combined with Weicao Capsule in the Treatment of Gout[J];Medical Journal of Wuhan University;2009-02
10 JI Jia-min1,MA Jia-hai1,LI Yu-hang1, ZHANG Tian-fu1,LIN Qiu-sheng1,WANG Min2(1 Key Laboratory of Aquatic Genetic Resources and Aquacultural Ecology Certificated by the Ministry of Agriculture,Shanghai Fisheries University,Shanghai 200090,China;2 Ocean Environmental Monitoring Centre of Lianyungang,Jiangsu Province,Lianyungang 222042,China);Isomorphic alternation of generations of Ulva pertusa[J];Fishery Modernization;2008-02
China Proceedings of conference Full-text Database 1 Hits
1 LI Li~(1,2),CHEN Ke-li~1,XU Jia-cheng~1,LEI Xiang~1 (1.Key Laboratory for Traditional Chinese Medicine Resource and Compound Prescription of Ministry of Education,Hubei College of Traditional Chinese Medicine,Wuhan 430065,China; 2.Key Laboratory for Green Chemical Process of Ministry of Education,Wuhan Institute of Technology, Wuhan 430073,China);Inhibition of Xantine Oxidase by the biflavonoids from the medicinal plant of Selaginella labordei[A];[C];2008
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 J I A N G Yiqiang , L I Shan , W U Chuang , et al.( 蒋一强,等) Affiliation hospital , Guangxi Medical University( 南宁 530021);Morpho metrical study on inhibitory effect of corn sti g maand banana - stem extract on calciu m crystalization[J];JOURNAL OF CHENGDU UNVERSITY OF TARDITIONAL CHINESE MEDICINE;1999-03
2 SHANG Yan-jun~(1),GUO Yue-wei~(2),HUANG Cai-guo~(1*),JIA Rui~(2),XU Qiang-zhi~(1),WEI Shan-jian~(1),JIAO Bin-hua~(1),ZHANG Jian-rong~(3) (1.Department of Biochemistry and Molecular Biology,College of Basic Medical Sciences,Second Military Medical University,Shanghai 200433,China;2.Shanghai Institute of Materia Medica,Shanghai 201203;3.Department of Clinical Laboratory,Changhai Hospital,Second Military Medical University,Shanghai 200433);Inhibition of xathine oxidase by renierol extracted from South China Sea sponge[J];Academic Journal of Second Military Medical University;2006-01
3 SHANG Yan-jun~(1),HUANG Cai-guo~(1*),JIANG San-hao~(2),ZHU Da-yuan~(2),WEI Shan-jian~(1),JIAO Bin-hua~(1)(1.Department of Biochemistry and Molecular Biology,College of Basic Medical Sciences,Second Military Medical University,Shanghai 200433,China;2.Shanghai Institute of Materia Medica,Shanghai 201203);Inhibition of xathine oxidase by rosmarinic acid[J];Academic Journal of Second Military Medical University;2006-02
4 LI Zhong-qin1,XU Xiao-ping2 and WANG Wu*1(1.The Key Laboratory of Industry Biotechnology,Ministry of Education,Southern Yangtze University,Jiangsu 214036;2.College of Chemistry and Chemical Engineering,Fuzhou University,Fujian 350002),Fenxi Shiyanshi,2007,26(8): 41~44;Determination of xanthine oxidase activity from Arthrobacter sp.by high performance liquid chromatography[J];Chinese Journal of Analysis Laboratory;2007-08
5 Liang Liyan, Deng Songzhi (Guangzhou Institute of Chemistry,Chinese Academy of Sciences,Guangzhou,510650,China);Progress in the Chemical Constituents of the Marine Sponges from South China Sea[J];GUANGZHOU CHEMISTRY;1999-02
6 NAN Chunrong1, 2, ZHANG Haizhi+1, DONG Shuanglin+2 (1. Department of Biology, Weifang University, Weifang\ 261043; 2. Aquaculture Research Laboratory, Ocean University of China, Qingdao\ 266003);Growth inhibition of queous extracts of Ulva pertusa on three species of microalgae in red tide[J];Acta Scientiae Circumstantiae;2004-04
7 Xu Shenhong, Hang Hu, Li Yunping\%;Study and Improvenment on the Pyrogallol Autoxidation Assay Method for SOD Activity Assay[J];Chemistry;2001-08
8 Mao Wenjun; Guan Huashi; Li Bafang(Marine Drugs and Foods Institute, Ocean University of Qingdao, Qingdao);DETERMINATION OF SELENIUM CONCENTRATION IN SEVERAL MARINE ORGANISMS[J];Transaction of Oceanology and Limnology;1995-04
9 LI Xian-Cui,FAN Xiao,HAN Li-Jun,YAN Xiao-Jun,LOU Qing-Xiang (Institute of Oceanology,The Chinese Academy of Sciences,Qingdao,266071);FATTY ACIDS OF COMMON MARINE MACROPHYTES FROM THE YELLOW AND BOHAI SEAS[J];Oceanologia Et Limnologia Sinica;2002-02
10 XU Xiu Li, FAN Xiao  , SONG Fu Hang (Institute of Oceanology, Chinese Academy of Sciences,Qingdao, 266071; Graduate school of the Chinese Academy of Sciences,Beijing, 100039)  (Institute of Oceanology, Chinese Academy of Sciences,Qingdao,266071);STUDY ON BIOACTIVITY OF CHINESE MARINE ALGA EXTRACTS[J];Oceanologia Et Limnologia Sinica;2004-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved