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《Qianwei Journal of Medicine》 2002-01
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Clinical and pathologic study on compensated liver cirrhosis of 548cases

Gan Tianfu,Zhang Guangshu,Du Qingling,et al.The88th Hospital of PLA,Taian271000,China  
Objective To evaluate the relationship between the clinical manifestations and hepatopathol-ogy of liver cirrhosis and treatment results with Tailai peptide,548patients with liver cirrhosis were studied.Methods All the studied patients were given liver biopsies,325more than two times.Liver tis-sues were studied with HE and Foot silver stains,HBVM and HBV DNA were detected with ELISA and PCR respectively.All the patients were treated in hospital for3to18months,6months on an average.Most of them were treated with Tailai peptide2to8ml i.monce daily,the others combined with lamivu-dine for3months.Results The studies showed that the clinical recovery rate was72.9%,ALT normal-ization rate98.6%and A/G improvement rate68.6%.The hepatopathology of most patients were im-proved obviously,disappearance of pseudolobules and intralobular fibrous septum to chronic active or per-sistent hepatitis was68.4%and34.6%respectively.Seroconversion rate of HBeAg and HBsAg was51.2%and7.5%respectively.Conclusions The pathological morphology of compensated liver cirrhosis can be reversed with correct effective treatment.Tailai peptide has excellent effects in treating liver cirrhosis
【CateGory Index】: R575.2
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