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《Practical Journal of Medicine & Pharmacy》 2010-01
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Effect of acute hypervolemic hemodilution on body internal environment homeostasis:Comparative study on different agents

LI Qian-hui,WANG Ling,WU Qing-hua,et al.Dept.of Anesthesia,No.150 Hospital,Luoyang,Henan 471031,China  
Objective To compare the effects of acute hypervolemic hemodilution by Lactated Ringer's solution、6% Hydroxyethyl Starch130/0.4 and 4% Succinylated Gelatin on body internal environment homeostasis.Method Thirty patients undergoing scheduled meningioma operation were randomly divided into 3 groups:Group Ⅰ(AHHD with lactated Ringer's solution),Group Ⅱ(AHHD with 6% hydroxyethyl starch 130/0.4),Group Ⅲ(AHHD with 4% succinylated gelatin),with 10 in each group.AHHD was performed by infusing 20 ml/kg·h solution 30 minutes before induction and infusing 20 ml/kg·h solution 30 minutes during and after induction,then the operation was performed.The venous blood samples were collected before AHHD(T1),at the end of AHHD(T2),60 minutes after AHHD(T3),120 minutes after AHHD(T4)respectively for determining HCT,HB,PT,TT,APTT,FBG,Ⅷ,VWF and β2-MG;arterial blood samples before AHHD(T1),at the end of AHHD(T2),60 minutes after AHHD(T3),120 minutes after AHHD(T4)were respectively collected for determining blood gas and electrolytes.Result In changes of HCT,HB there were significant differences between after AHHD and before AHHD(P0.01);in changes of PT,TT,APTT,FBG,Ⅷ,VWF there were significant differences between after AHHD and before AHHD(P0.05),and TT,FBG,Ⅷ,VWF were all at the normal level,but PT,APTT were beyond the normal level;in changes of APTT there were significant differences between group Ⅱ,Ⅲ and groupⅠ(P0.01).In changes of β2-MG,compared with T1,there were no significant differences at T2,T3,T4(P0.05);in changes of pH and K+,compared with T1,there were no significant differences at T2,T3,T4(P0.05),compared with T1,HCO3-,PaCO2 decreased significantly after AHHD(P 0.01).Compared with T1,Na +,Cl-increased significantly at the end of AHHD(P0.01);Ca2+ decreased significantly at the end of AHHD in group Ⅱ and group Ⅲ(P0.01).Conclusion AHHD before operation can maintain stable hemodynamics;AHHD with 6% hydroxyethyl starch 130/0.4 and 4% succinylated gelatin have effects on blood coagulation,but no clinical hemorrhagic signs increased.AHHD with 6% hydroxyethyl starch 130/0.4 and 4% succinylated gelatin have no determental effects on renal function in patients with normal function.AHHD has no significant effect on the analysis of blood gas;After AHHD Cl-increased in three groups,and Ca2+ decreased in groupⅡ and groupⅢ,which attentions should be taken and supplement of Ca2+ is necessarily given.
【CateGory Index】: R614
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 XU Yong-guang,WANG Xiao-yan,LI Gang;Effect of AHHD on hemodynamics,electrolytes andarterial blood gas in patients receiving scheduledgastrointestinal surgery[J];Shandong Medical Journal;2006-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 GUO Xiao li,GE Heng jiang, LIU Huai qiong (Department of Anesthesiology, Daping Hospital, Third Military Medical University, Chongqing 400042,China);Hemorheologic changes after with HES:an in vitro study[J];Journal of Traumatic Surgery;2001-04
2 CHEN Xiaopeng;LIU Zhongjin;ZHOU Guang,et al (YiJishan Hosptial,Wannan Medical College,Wuhu 241001);A Clinical study on indomethacin improving renal dysfunction of obstuction jaundice[J];JOURNAL OF HEPATOBILIARY SURGERY;1997-05
3 Li Zhigui,Ma Weiqing,Huang Haibo,et al. Department of Anesthesiology,Kunming General Hospital of Chengdu Military, Kunming 650032 CHINA;The protective effects of propofol on renal function injured by infrarenal aortic cross clamping in rabbits[J];The Journal of Clinical Anesthesilolgy;2001-10
4 Yu Qinzhong et alLi Yang People's Hospital, Jiang Su(213300);Treatment with Haemaccel for Hypovolumetric Shock[J];Clinical Medical Journal of China;1998-03
5 Wang ZhongYue,et al;The protective effect of acute isovolemic hemodilution on renal function during controlled hypotension[J];Zhejiang Clinical Medical Journal;2004-11
6 Yang Mu Huang MingzhiBeijing University of Chemical Technologjr,Beijing 100029;Plasma substitutes of gelatin solution[J];The Ccience and Technology of Gelatin;2001-03
7 Ning Jishun,Yue Yun,Tang Zhenshen,et al.Department of Anesthesia,General Hospital of Jinan Military Region,Jinan250031,China;Effect of hydroxyethyl starch on blood circulation in the replantated figures[J];Qianwei Journal of Medicine;2002-10
8 Guo Xiaoli,Ge Hengjiang,Liu Huaiqiong.Department of Anesthesiology,Daping Hospital,Third Military Medical University,Chongqing,400042;Effect of hydroxyethyl starch on hemorheology in patients with surgical operation[J];Sichuan Medical Journal;2001-02
9 Ji Yong, Zhang Tong, Wang Baoguo, Zhao Fenghua, Wang Enzhen Department of Anesthesiology, Beijing Tiantan Hospital, Affiliate of Capital University of Medical Sciences;Changes of Coagulation and Electrolyte during Hypervolemic Hemodilution[J];Journal of Capital University of Medical Sciences;2001-02
10 WANG Ting-song, LU Yi-ming, DAI Ran-ran, CAO Ming, LU Zhi-jun, YU Bu-wei (Department of Emergency, Department of Anesthesiology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025 , China);Therapeutic Effect of Hypertonic Sodium Chloride Hydroxylethyl Starch 40 on Hemorrhagic Shock[J];Acta Universitatis Medicinalis Secondae Shanghai;2005-03
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Ma Wei,Xu Haifang,Zhou Shu,et al. Department of Anesthesiology,Ruijing Hospital,Shanghai Second Medical University,Shanghai 200025 CHINA;Influence of acute hypervolemic hemodilution on thoracic electrical impedance[J];The Journal of Clinical Anesthesilolgy;2002-02
2 Xu Yongguang,Li Gang,Yangmiao,et al;A study of the optimal dosage of midazolam in anesthetic induction combined with propofol, fentanyl and vecuronium[J];Shandong Medical Journal;2003-35
3 DONG Qinglong, WEN Xiaohui, OUYANG Baoyi Department of Anesthesiology, First Affiliated Hospital of Guangzhou Medical College, Guangzhou 510120,China;Hemodynamic and hemorheological effects of hypovolemic hemodilution with hydroxyethyl starch[J];Chinese Journal of Anesthesiology;2001-05
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