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《Practical Journal of Medicine & Pharmacy》 2015-01
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Experimental study:influence of resonance at constrained body posture on histomorphology of intervertebral discs

ZHANG Zhi-hui;HUANG Chang-lin;WANG Shuai;Whole-army Institute of Military Training Related Medical Science,No.150 Hospital of Chinese PLA;  
Objective To analyze the effect of resonance at constrained body posture on histomorphology of rabbit intervertebral discs,and investigate the mechanism of vibration with different frequencies effecting on the rabbit intervertebral discs. Methods Ninety healthy rabbits were randomly divided into 5 groups(n=18). Group A as normal group;Group B as control group;Group C as 4 Hz vibration group;Group D as 5 Hz vibration group;Group E as 6 Hz vibration group. L5 / 6 intervertebral discs of six rabbits were extractioned at 2,4,8 week in each group randomly. Changes of intervertebral discs in histomorphology were observed in different time points,and pathological grades were recorded. Results Pathological changes of nucleus pulposus in vibration groups were earlier than that in normal and control group,and pathological grade in 6 Hz vibration group was obviously higher than that in other groups, which advanced with time.There were no significant difference between 4 Hz vibration group and control group in pathology of nucleus pulposus. Conclusion Dynamic stress caused by vibration can easily induce the harmful pathological changes of nucleus pulposus,and appearance of resonance effect will lead to a grave destroy.
【Fund】: 全军“十一五”医学科技研究课题(06MB128)
【CateGory Index】: R82
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