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《Practical Journal of Medicine & Pharmacy》 2015-01
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Influence of syntony on the serum bone metabolism markers of rabbits at forced posture

XVE Gang;HUANG Chang-lin;WANG Qian-jin;Whole-army Institute of Military Training Related Medical Science ,No.150 Hospital of Chinese PLA;  
Objective To observe the influence of the syntony from 4 Hz to 6 Hz on the bone metabolism markers in serum such as alkaline phosphatase(levels of BALP),osteocalcin(BGP) and tartrate-resistant acid phosphatase(TRACP) in rabbits at forced posture. Methods Sixty New Zealand white rabbits were randomly divided into five groups: control group,matched control group,4Hz model group,5Hz model group and 6Hz model group. The activity of the bone alkaline phosphatase(BALP),bone gla protein(BGP) and tartrate-resistant acid phosphatase(TRACP) in serum were determined at the 2nd,4th and 6th week after experiment. Results Compared with the normal control group,BALP in the matched control group ascended at the 6th week,TRACP were elevated since the 4th week and BGP began to descend at the 4th week(P0.05). Compared with normal control group,BALP in the 4Hz,5Hz and 6 Hz model group were elevated since the 4th week,TRACP began to ascend at the2 nd and BGP began to descend at the 2nd week(P0.05). Compared with the normal control,BALP in the 5Hz and 6Hz model group began to ascend at the 6th week(P 0.05),TRACP began to ascend and BGP began to descend at the 2nd week(P0.05). The content of TRACP in the 4Hz model group was higher than that in the5 Hz and 6Hz model group at the 2nd week and 4th week(P0.05). Conclusion The serum markers about bone metabolism are useful to early diagnosis of bone injury.
【Fund】: 全军“十一五”医学科研基金(06MB128)
【CateGory Index】: R82
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