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《Practical Journal of Medicine & Pharmacy》 2015-01
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The best time point of implant surgery after low dose irradiation:An experimental study

LIU Yu-xiao;YU Shu-juan;LIN Fei-fei;Department of Stomatology,the General Hospital of Jinan Military Region;  
Objective To explore the best time point of implant surgery in dog mandibles after low dose irradiation. Methods Ten Chinese dogs were randomly divided into four groups three months after the extraction of their unilateral posterior teeth. Group1,2,3(3 dogs for each),as experimental groups;rest one dog as control group,i. e group 4. They all received unilateral irradiation with60 Co in the defect parts of mandible with a total dose of 22.8Gy in four 5.7Gy fractions(biologically equivalent to 50 Gy / 25 fractions);group 4 without irradiation.Then three time points were chosed to conduct implant surgery in group 1,2,3 individually:One month,three months,six months after irradiation;meanwhile group 4 also received implant surgery though without irradiation.After six months,all the animals underwent X-ray and regular inspection of the implant so as to analyse the difference of each time points;vertical bone lose around the implant in all the groups were observed. Results There were significant difference between group 1 and other three groups. Group 1 was more apparent than other groups;there was no difference between the rest every two groups. Conclusion Three months after irradiation is the best time-point for implant surgery.
【CateGory Index】: R783.6
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