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《Practical Journal of Medicine & Pharmacy》 2015-03
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Protective effect of ambroxol hydrochloride on flail chest patient's lung and respiratory function at perioperation

BAI Chong-feng;WANG Yun;FAN Shao-wei;Department of Cardiothoracic Surgery,No.401 Hospital of Chinese PLA;  
Objective To observe the protective effect of ambroxol hydrochloride on lung and respiratory function at perioperative period of flail chest. Methods Seventy-two patients with flail chest were randomly divided into two groups(n=36,for each). At their perioperative period,the patients of ambroxol group were treated with ambroxol hydrochloride on the basis of the conventional treatment of control group. The changes of sputum and its expectoration,the days of using antibiotics and incidence of pulmonary complications were compared between both groups. Results Compared with control group,the patients treated with ambroxol got a better result.The sputum and its expectoration were improved,the days of using antibiotics was shortened,and incidence of pulmonary complications was reduced. The differences were significant statistically(P0.05). Conclusion Perio-perative use of ambroxol hydrochlorid for flail chest patients is worthy clinically to improve respiration and reduce pulmonary complications.
【Fund】: 青岛市卫生科技计划项目(2012-WSZD133)
【CateGory Index】: R655
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