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《Practical Journal of Medicine & Pharmacy》 2015-08
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The application methods of platelet-rich plasma(PRP) in the treatment of burns,and the evaluation of it value

LI Bin;ZHANG Ke-yan;The Hospital of Provincial Public Security Fire Fighting Corps;  
Objective To explore the platelet-rich plasma(PRP) application methods and applications value in burn. Methods The 66 deep Ⅱ degree burns patients were randomly divided into PRP group and control group;the control group received medication plus local dressing exchange,the PRP group received medication plus local dressing exchange and PRP external use. Then two groups were compared in granulation tissue maturity,wound healing time,serum concentrations of VEGF,serum concentrations of TGF-β1. Assessing the value of PRP in the treatment of burns was taken. Results PRP could significantly shorten the healing time of wounds;in PRP group at 5 d and 10 d after treatment,the maturity of granulation tissue were significantly greater than in the control group;in PRP group the concentration of VEGF and TGF-β1 in serum at 5 d and 10 d after treatment was significantly higher in the control group. Conclusion PRP has very significant effect and application value in the treatment of burns.
【CateGory Index】: R644
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