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《Practical Journal of Medicine & Pharmacy》 2015-12
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Searching for the unknown primary lesion of hepatic metastatic carcinoma

LI Yue-kai;LI Feng-cai;LIU Jian-feng;Qilu Hospital of Shandong University;  
Objective To investigated the clinical value of ~(18)F-FDG PET-CT whole body imaging in searching for primary lesions of hepatic metastatic carcinoma. Methods The 113 patients(male 61 cases,female52 cases) with liver metastasis,had received conventional imaging examination(such as ultrasonic,CT,MRI etc).But the primary lesions were not correctly located. Then the ~(18)F-FDG PET-CT whole body scan was conducted and estimated the standardized uptake value(SUV) of the suspicious primary lesion. All PET-CT diagnosis of primary lesions were compared with pathology or clinical follow-up of more than half a year. Results The true positive rate of PET-CT diagnosis of hepatic metastatic carcinoma with unknown primirary site was 78.76%,false positive rate was 7.08%,true negative rate was 5.31%,false negative rate was 8.85%,the diagnostic accuracy was 84.07%. The primary tumor sites of true positive group mainly located in gastrointestinal organs and lung,but the standardized uptake values(SUV) of different primary lesions were not statistically significant. Conclusion For hepatic metastatic carcinoma unknown primary site ~(18)F-FDG PET-CT has incportant clinical diagnosis value.
【CateGory Index】: R735.7
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