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《China Tropical Medicine》 2001-01
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Study on the Relationship between Infantile Cerebral Palsy and Toxoplasmosis

HUANG Mei-jiao, FANG Yin-huai ,YUAN He-qiu (Hainan Provincial People' s Hospital , Haikou 570311.)  
Objective To explore the relationship between unknown infantile cerebral palsy and toxoplasmosis in Hainan Province and offer basis for diagnosis and treatment of infantile cerebral palsy. Methods The admitted infants diagnosed as unkown cerebral palsy were taken as the experimental group and the healthy infants by plysical examination were taken as control. Detection of anti-toxoplasma gondii antibodies of IgG and 1gM, circulating antigens(CAg) and DNA was conducted and the relationship between infantile cerebral palsy and toxoplasmosis were compared and analysed. Results Among the 79 infants with cerebral palsy in the experimental group, 33 infants were detected to be infected with toxoplasma gondii giving an positive rate of 41 .8% ;23 positives were detected out of the 269 infants in the control group with an infective rate of 8.6%. significant difference was observed in the tow groups(P 0.01) Conclusion The infection with toxoplasma gondii is one of the leading cause resulted in the unknown infantile cerebral palsy in Hainan, the detection of toxoplasmosis in the pregnants, new-borns and babies/infants should be one of the measures in preventing the occurrence of infantile cerebral palsy.
【CateGory Index】: R742.3;R725.3
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