A Case with Translocation of Chromosomes 3;11 and Deletion of Bands 11q24 to 11qter
Lin Ruidong Gong Rong Xiao Sheng'e Deng SujianDapartment of BiologyWu YongshangDepartment of Paediatrics,Affiliated Hospital
This paper reports a female infant with congenital mental deficiency, transverse palm-ar creases, poor sight, motor and mental retardation. The cultures of peripheral blood and G-banded analysis showed the karyotype of 46,XX, t (3;11) (3qter→3p21::11pl4 →11pter; 11p14→11q24::3p21→3pter), del (11q24→11qter). This female infant had the clinical symptoms similar to those of 11q partial monosomy syndrome. It was thus believed that unbalanced translocation of chromosomes was one of the causes of congenital malformation.