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《JOURNAL OF GUANGZHOU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE》 2000-03
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Inhibitory Effect of Liuwei Dihuang Decoction on Lymphocyte Apoptosis in Immune Organ of Glucocorticoid_induced Kidney_yin_deficiency Animal Model(Ⅱ)

XU Qin, DU Biaoyan, LUO Hui, SU Junfang, WU Shaofeng (Dept. of Pathology, Guangzhou University of TCM, Guangzhou 510405, China)  
To further explore the immunological mechanism of kidney_yin_deficiency syndrome, NIH mice were allocated to three groups: normal control group, model group and Liuwei Dihuang Decoction (LDD) group. Apoptotic T lymphocyte in lymphatic sheath around splenic artery was detected with in situ end labeling technique after medication for 6 days. The results showed that the number of apoptotic T lymphocytes was more in the model group than that in the normal group, and much less in LDD group than that in the model group (P 0.05 ). This indicates that LDD with the action of nourishing Yin and tonifying kidney can antagonize T lymphocyte apoptosis induced by glucocorticoid.
【Fund】: 广东省中医药管理局课题! (NO . 970 72 )
【CateGory Index】: R285
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