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Technology and Biological Application of Surface Plasmon Resonance Biosensor

MENG Qing-shi~(1,3) LAO Wen-yan~2 PAN Ying-hong~3(1、College of Life Science,Sichuan Normal University,Chengdu,610000,China;2、Beijing Pharmaceutical College,Beijing,10012,China;3、The National Key Facility for Crop Gene Resources and Genetic Improvement(FCRI),Institute of Crop Science,Chinese Academy of Agricultural Sciences(CAAS),Beijing 100081,China)  
Surface plasmon resonance(SPR)is a phenomenon which occurs when light is reflected offthin metal films.Based on this phenomenon, some SPR biosensors have been developed and been extensively used for characterizing and quantifying hiomolecular interactions.In this paper,the working principles,technical parameters and test method for SPR biosensors are discussed.The main applications of SPR biosensors teleology in life science field,such as immunodetection,drug metabolism,protein dynamics,are also described.
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