Comparative Research of between Autologous-injected Model and Collagenase-injected Model about Intracerebral Hemorrhage in Rats
Deng ShishanWang SongZhang BensiWang ZhongliangZhou Deming (Department of Anatomy, School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China)
Objective This experiment supplies and data concerned for the research of pathologic mechanism and therapy of intracerebral hemorrhage. Methods We had respectively injected autologous blood 50μl and bacterical collagenase 0.3units into the right caudate nucleuses in rats to make two different kinds of disease animal model.ResultsObvious difference have been between two different model which are the volume of hematoma, the volume of edema, the occurring mechanism of hematoma, the histopathologic exhibition and neurologic function's behave.Conclusion Because we can adopt a suitable model for research according to researching purpose and to different data grom two animal models.
【CateGory Index】： R-332