MicroRNA Biological Function and Mechanism of its Action in Tumor
Chen Guoqing1 Zhao Zhiwei2 Cao Xia2 Yang Huijun21 (College of Health Science,Wuhan Sports University,Wuhan 430079,China)2 (Department of Anatomy,West China School of Preclinical and Forensic Medicine,Sichuan University,Chengdu 610041,China)
MicroRNAs are small noncoding RNAs that function to regulate gene expression by posttranscription regulation or degradation mRNA of target gene. MicroRNAs play important roles in homeostatic processes such as development,cell proliferation,cell apoptosis and energy metabolism and link to the development of the cancer,diabetes,cardiovascular disease and nervous system disease. In this review,we describe the function and mechanisms of microRNA involved in tumorigenesis and tumor growth.