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《Sichuan Journal of Anatomy》 2012-01
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Brain Iron Metabolism:Cerebral Ischemia and Neurochemistry

Xiu Lili Wang Wei 1(Department of Human Anatomy and Histology and Embryology,Fujian Medical University,Fuzhou 350004,China) 2(Neurobiology Research Center,Fujian Medical University,Fuzhou 350004,China)  
The accumulated evidence demonstrates that misregulation in brain iron metabolism is one of the initial causes for neuronal death in cerebral ischemia..Iron metabolic disorder usually happens following acute cerebral ischemia,which leads to excess free radical and iron ion accumulation and ultimately accelerate the cerebral injury.Research on the changes and mechanism of iron ion metabolic imbalance in brain will help us to find nosogenesis of cerebral ischemia injury and effective treatment thereafter.In the article,the recent advances in studies on neurochemistry and neuropathophysiology of brain iron metabolism and possible mechanism were reviewed.
【CateGory Index】: R743.3
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Li Yanwei1,Zhao Jinying1,Huang Jun1,Li Lin2 (1.Department of Human Anatomy,Shaoyang Medical College,Shaoyang 422000;2.Key Laboratory of Cellular Physiology of the Ministry of Education,Shanxi Medical University,Taiyuan 030001,China);A study of the increase of divalent metal transporter-1 expression induced by cerebral ischemia in the cortex and hippocampus of rats[J];Chinese Journal of Neuroanatomy;2011-03
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 LIU Shuxin,LIU Yuqian,WANG Haitao,QIN Chun,LIANG Guobin,ZHAO Bin(College of Physical Education,Hebei Normal University,Hebei Shijiazhuang 050024,China);Effect of Hepcidin on Cellular Iron Metabolism[J];Journal of Hebei Normal University(Natural Science Edition);2011-01
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 LI Yan-wei~* QIAN Zhong-ming LI Lin~*.* Institute of Gerontology,Shanxi Medical University,Taiyuan 030001,China;Acute cerebral ischemia and iron metabolic disorders[J];Chinese Journal of Neuromedicine;2007-04
2 Shen Hong(The First Military Medical University,Guangzhou,510515);STUDY ON THE QUANTITATIVE METHOD OF IMMUNOHISTOCHEMISTRY(Ⅲ)[J];CHINESE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY;1995-01
3 KE Ya, QIAN Zhong Ming ** (Laboratory of Iron Metabolism, Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China);Divalent Metal Transporter 1: A Newly Discovered Mammalian Iron Transport Protein[J];Progress In Biochemistry and Biophysics;2002-02
4 JIANG Hong;QIAN Zhong-Ming;XIE Jun-Xia Department of Physiology,Medical College of Qingdao University;Neuroscience Center of Shandong Province,Qingdao 266021 Department of Applied Biology and Chemical Technology,Polytechmic University of Hong Kong;Increased DMT1 expression and iron content in MPTP-treated C57BL/6 mice[J];Acta Physiological Sinica;2003-05
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