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《Sichuan Journal of Anatomy》 2013-03
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Research Advancement of miR-93 and Cancer

Liu Geng;Zhou Hongying;West China School of Preclinical and Forensic Medicine,Sichuan University;  
It has been revealed that microRNA(miRNA)expression contribute to the initiation and progression of cancer.Among them,deregulated expression of miR-93play critical roles in cell proliferation,apoptosis,migration and differentiation.miR-93may promote potential proliferative,anti-apoptotic and drug-resistance effects via binding to PTEN,E2F1,Six1and any other genes.miR-93can additionally target the inhibitory Smad7to induce EMT,which may be a potential oncogene.
【CateGory Index】: R730.2
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