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Research Development of Mir-30

Yi Tao;Gynecological Oncology of Biotherapy Laboratory,West China SecondHospital,Sichuan University;  
MicroRNAs(microRNAs,miRNA)is a small non coding endogenous RNA,performing post-transcriptional regulation of gene expression,which is one of the most important discovery of molecular medicine.Although thousands of miRNA has been found at present,and the functions of many miRNAs have been reported in previous studies,the functions of the majority of miRNAs remain poorly understood.MiR-30family members have been identified associate with a variety of physiological processes.Thus miR-30may serve as a potential indicator of disease presence but more importantly,may have a role in disease characterization or as a potential therapeutic target.This review gives a brief overview of miR-30biochemistry and explores the evidence to date implicating this small molecule in the pathogenesis of tumors.
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