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《Sichuan Journal of Anatomy》 2014-01
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The Research Progression of Claudins in Ovarian Cancer

Liu Lili;Zhao Xia;Department of Gynecology and Obstetrics,West China Second University Hospital,Sichuan University;  
Claudins are a family of proteins forming the backbone of tight junctions.Abnormal expression of claudins is frequently observed in malignant tumors,and it may be related to tumor cell adhesion,proliferation and invasion.In recent years,researchers have used claudins as new targets in cancer therapy.Meanwhile,due to the abnormal expression of claudins in tumor tissue,claudins may become new molecular markers for tumor diagnosis and evaluation prognosis.Claudins have become the hot item of cancer research.In this article,we reviewed current progress in the research on claudins in ovarian cancer.
【CateGory Index】: R737.31
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