INFLUENCE OF VASECTOMY TO THE EXPERIMENTAL RABBIT ATHEROSCLEROSIS
Liu Shicang; He Caichun; Tang Guanhwa(West China University of Medical Science, Sichuan Family Planning Research Institute Chengdu 610041)
Twenty Japanese white rabbits were divided into A, B, C, D four groups. There are five animals in each group. The rabbits of Group A and B were used for vasectomy. Twenty weeks post-vasectomy, the rabbits of group B and C were fed with high-fat diet through twenty-five weeks. Group D was used for control. Rabbits of each group were sacrified in the same time. Pathologic investigations showed that sperm stasis, intestitial lymphocytic infiltrations and sperm-granulomas were found in epididymis of vasectomised groups (A, B).There were three vasectomised (B) and two non-vasectomised (C) rabbits showed macroatherosclerotic lesions in aorta and common carotid artery in rabbits with high fat diet. Microscopically.all of the ten rabbits of B, C group showed lipoid deposition and active phagocytosis,but there were no apparent difference between the two groups. The result of this priliminary study shows that the sperm immunity does't influence the formation of atherosclerosis.