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Study on the Mutation of Erythromycin Productive Strain and Its Fermentation

ZUO Yong,LI Yang,REN Yong-li,JU Shuai,XIE Hui,QI Feng(School of Biotechnology Engineering,Sichuan University of Science & Engineering,Zigong 643000,China)  
The Saccharopolyspora erythraea 08L is used as the starting strain.Processed by ultraviolet mutagenesis,the fermentation product of the mutated strains was increased by 12.6%.In addition,under the optimized culture medium which consisted of starch 3%,dextrin 3%,glucose 2%,soybean meal 3%,corn steep liquor 1%,(NH4)2SO4 0.15%,CaCO30.6%,KH2PO40.02%,the fementation yield of UL5 strains was increased by 15.2%.
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