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Measurement of Interleukin 6(IL-6) in Vitreous of Proliferative Vitreoretinopathy

Hu Jianbing,Yu Yufeng,Fan Yingchuan∥Sichuan Peoples Hospital,610072  
Objective:To investigate the expression of Interleukin 6(IL 6) in vitreous of proliferative vitreoretinopathy(PVR),analyse the function of IL 6 in PVR.Methods:The level of IL 6 in vitreous were measured by ELISA method in 37 proliferative vitreoretinopathy cases and 12 normal cases.Results:The IL 6 level in vitreous of 32 PVR was 264.87±136.41pg/ml,IN which the IL 6 in retinal detachment PVR was 261.41±131.27pg/ml,in traumatic PVR was 297.97±141.53pg/ml.Normal contrast IL 6 35.69±20.64pg/ml.The level of IL 6 in vitreous of PVR was higher than normal contrast ( P 0.01).And IL 6 in grade C、D PVR was higher than grade A、B PVR.Conclusion:The expression of IL 6 in vitreous of PVR is up going,and IL 6 participate in the occurrence and development of proliferative vitreoretinopathy.IL 6 may play a main role in the latesed stage of PVR.
【CateGory Index】: R776.4
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