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《Sichuan Journal of Physiological Sciences》 2013-01
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Effect evaluations of urokinase in tube sealing for permanent cuffed catheter in hemodialysis patients

Liao Song-qing(Department of Nephrology,The Sixth People′s Hospital of Chengdu,Sichuan Chengdu 610051)  
Objective: To explore the effect of urokinase in tube sealing for permanent cuffed catheter in hemodialysis patients.Methods: 27 hemodialysis patients were randomly divided into 3 groups: urokinase group(n=9),heparin group(n=9) and urokinase+heparin group(n=9).All kinds of clinical indexs were observed and compare with different groups after 6 months.Results: Compared with heparin group,case numbers of catheter unobstructed degree and dialysis blood flow were signigicantly increased(P0.05);numbers of single suction catheter impeded,arteriovenous reverse connect and nursing intervention were significantly reduced(P0.05).Moreover,there were no markedly differences as compared to urokinase+heparin group(P0.05).Conclusion: Regular use of urokinase sealing tube can be effectively used for permanent cuffed catheter in hemodialysis patients.
【CateGory Index】: R472
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