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《Journal of Sichuan of Traditional Chinese Medicine》 2006-01
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Impact of Herba Cirsii extracts on hemorrhage,blood coagulation and experimental inflammation in Rats

Yang Xinghao Cui Jinghao Ding Anwei.∥College of Pharmacy,Nanjing University of Traditional Chinese Medicine(Nanjing Jiangsu 210029)  
Objective:To investigate the effects of different extracts from Herba Cirsii on hemorrhage,blood coagulation and experimental inflammation in rats.Methods:The coagulation time was measured by using capillary method;the bleeding time was measured using tailcutting method.The rat model for experimental inflammatory was established by the way of rat ear swelling.Results:The flavonoids,the ethyl acetate extract and nbutanol extract of decoction significantly shortened the time of hemorrhage and blood coagulation time,flavonoids significantly inhibited the rat ear swelling,compared with the control group.Conclusions:The flavonoids,ethyl acetate extract and n-butanol extract of the decoction Varry their actions on stopping hemorrhage,blood coagulation,and anti-inflammation.
【Fund】: 国家十五攻关科技专项基金资助课题(2001BA701A55-40)
【CateGory Index】: R285.5
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