Effect of ShanTangPing on bloodfat in hyperlipoidemia model of rat
Niu Na Li Yan Wu Chongming Wang Kun Wang Yanlin Pan Jingmiao Qin Jian.School of life and science & technology in Beijing institute of technology(Beijing 100081)
Objective:To observe the effect of ShanTangPing on blood lipid and lipoprotein concentration in rats with hyperlipidemia.Methods:The rats with hyperlipidemia model was established by feeding high-fat diet,the normal and negative control was clysterized with 0.5% CMC,the other treated groups was clysterized with Simvastatin 15mgkg and ShanTangPing(3200mgkg、1600mgkg、800mgkg)respectively,at 10d and 22d,the level of TC、TG、HDL-c were measured and calculated [LDL-c=TC-(HDL-c+TG5)],The liver and the fat of epididymis were weighed and the coefficient of liver and body fat were also calculated.Results:comparing with negative control,ShanTangPing at dose of 3200mgkg and 1600mgkg could decrease the level of serum TC,TG significantly,but were found no effect on other index.Conclusions:ShanTangPing could decrease the serum level of TC,TG in rats with hyperlipidemia.
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