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Effects of TCM Herbs on the activity of receptor tyrosine kinase in wound of soft tissue in mice.

Zhang Jianguo.Huzhou teachers college medical college(Zhejiang Huzhou,China 313000)  
Objective:To elucidate the changes of activity of receptor tyrosine kinase(RTK) in wound of soft tissue in mice after using Chinese Traditional Medicine Herbs(TCMH).Methods:Experimental trauma models of soft tissue were made on Kunming mice,those who given oral TCMH as the experimental group,and without TCMH as control group.The mice were sacrificed successively at 2nd,3rd,5th,7th,10th day after operation.The RTK activity in the wound were measured by using menbranous conjugated method.Results:The RTK activity in wound tissue of the experimental group was obviously elevated as compared with that of control group from 2nd day to 7th day(P0.01).RTK activity of wound tissue got near to the level of normal soft tissue at 10th day after operation.Conclusions:The TCMH could promote the activity of RTK of wound of soft tissue in mice.
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