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《Journal of Sichuan of Traditional Chinese Medicine》 2011-01
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Comparing the Differences among Patrinia scabra Bunge.Extractions Growth-inhibiting Effects of on Tumor Cell in Vitro

Chen Ru Zhao jianxiong Wang Xuexi 1.Guangxi College of Nursing of Traditional Chinese Medicine(Guangxi Nanni 530022,China) 2.Institute of the Combination of Traditional Chinese Medicine and Western Medicine in Lanzhou University(Lanzhou Gansu 730000,China)  
Objective:Comparing the differences among Patrinia scabra Bunge.extractions on growth-inhibiteng effects of tumor cell in vitro and testing anti-tumor effects of different Patrinia scabtra Bunge.extractions.Methods:The SPCA-1、HepG2、K562 cells growth was measured by MTT-microculture tetrazoliu assay.Results:Patrinia scabra Bunge.lignanoid、saponin inhibited the SPCA-1、HepG2、K562 cell growth in concentration-and time-dependent manners.And the effect of Patrinia scabra Bunge.lignanoid is more significant.IC50 is 21.16μg/ml after intervention in 400μg/ml Patrinia scabra Bunge.llignanoid for 96h,But polysaccharide has different effect on different tumor cell.Conclusions:The anti-tumor effect of different Patrinia scabra Bunge.extractions are distinguished from treating different tumor cell.The effect of Patrinia scabra Bunge liynanoid is more significant.
【CateGory Index】: R285.5
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