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《Shandong Journal of Biomedical Engineering》 2002-01
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Effect of Promoting Qi Activating Blood Circulation and Resolving Toxin Method in Protecting Vasculae Endothelium and Inhibiting Platelet Activation of UA Patients

Wang Xiangang 1 Zhang Wengao 1 Liu Jianping 2 Xie Qingcheng 3 Yin Geping 2 Liu Longtao 1 Xu Jun 2 1(Shandong University of Traditional Chinese Medicine, Jinan 250014) 2(Jinan General Military Hospital, Jinan 250031) 3(Secondary Hospital o  
This study was conducted to observe the effect of promoting QI activating blood circulation and resolving toxin method in protecting vascular endothelium and inhibiting platelet activation of UA patients. 43 cases of UA patients were divided into 2 treatment groups at random: pure west medicine group(control group) and promoting QI activating blood circulation and resolving toxin group(TCM group). Both groups were given the same west medicine routine regimen. TCM group was added with Astragale Injection(20ml iv.drip Qd; including Astragalus 40mg), Luotai Injection(Panax Notoginseng Saponins powder injection, 400mg iv.drip Qd), and Toxin-resolving Heart-protecting capsules(each grain includes super tiny crushed Coptis 0.4g and tea polyphenols 0.08g, 3 grains P.o Tid). The course of treatment was 2 weeks. 20 cases of healthy people were set as normal group. To detect CD 62p with flow cytometry, and detect vWF with ELISA. Statistical analysis were made in each group before and after the treatment. Results: CD 62p and vWF had no difference in both groups before treatment, and were higher than normal group(P0.01). After treatment, CD 62p and vWF reduced significantly in both groups, and TCM group was superior to control group.(P0.01). Conclusion: Promoting QI activating blood circulation and resolving toxin method reflected by the combination of Astragalus, Panax Notoginseng Saponins and Coptis had the effect of protecting vascular endothelium and inhibiting platelet activation remarkably.
【CateGory Index】: R259.4
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