Determination of Glipizide in Human Serum by High-performance Liquid Chromatography
Fu Shanji Liu Xiangqun Zhang Jian Wang Qian (Institute of Clinical Pharmacology,Qilu Hospital of Shandong University,Jinan 250012)
A high-performance liquid chromatographic method for the determination of glipizide in human serum has been developed.The glipizide were successfully seperated on a Lichrosorb Si60(5μm 150×4.6mm I.D)using methanol-water(50:50,volume ratio)as mobile phase at flow rate 1ml/min and detected at 275nm. This method is fast,sensitive,accurate and suitable for the analysis of tlipizide in serum and other samples.
【CateGory Index】： R969