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Studies on in vitro Dissolution Kinetics of α-TCP Bone Cement

DENG Min,SONG Zhi-guo,ZHENG Chang-qiong(Department of Biomedical Engineering, Sichuan University, Chengdu, 610065 China)  
Dissolution kinetics of α-Tricalcium phosphate (α-TCP) bone cement in physiological saline dissolution is studied in the present paper. It shows that the dissolution process of α-TCP bone cement in static physiological saline accords with Avrami kinetic model equation: -ln(1-x)= kt 1/2,its activation energy is about 9.87kJ/mol.The process is controlled by diffusion of forming hydroxyapatite (HA) solid layer.
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