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The influence of TGF-β on Biological Behavior of Rat Postnatal Dental Messenchymall Cells

YANG Wei;Guanganmen Hospital,China Academy of Chinese Medical Sciences;  
To investigate the effects of TGF- β on proliferation and differentiation of dental mesenchymal cells. The dental mesenchymal cells obtained from four- day postnatal SD rats were induced upon stimulation of TGF- β in vitro. MTT method and level detection of alkaline phosphatase were used to assess dose- effect and time- effect of TGF- β on the proliferation. TGF- β could significantly inhibit the proliferation and stimulation of dental mesenchymal cells. TGF- β can accelerate the proliferation and differentiation of dental mesenchymal cells.
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