The influence of TGF-β on Biological Behavior of Rat Postnatal Dental Messenchymall Cells
YANG Wei;Guanganmen Hospital,China Academy of Chinese Medical Sciences;
To investigate the effects of TGF- β on proliferation and differentiation of dental mesenchymal cells. The dental mesenchymal cells obtained from four- day postnatal SD rats were induced upon stimulation of TGF- β in vitro. MTT method and level detection of alkaline phosphatase were used to assess dose- effect and time- effect of TGF- β on the proliferation. TGF- β could significantly inhibit the proliferation and stimulation of dental mesenchymal cells. TGF- β can accelerate the proliferation and differentiation of dental mesenchymal cells.