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《Shanghai J.of Immunology》 1997-01
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A New W Box Sequence of HLA-DQA1~*0601 Gene Promoter in a Chinese Homozygous Cell SMY-43A

Huang Lidong, Lu Peihua, Lin Lin, Liu Yahe, Fu Saili and Chou Kuangyen (Sha-nghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025)  
For highly polymorphic HLA class D genes, transcription promoter re-gions are essential in determining the differential patterns of allelic expression in re-lation to their functions. A 318 base pair fragment of QAP (DQAl promoter) of a Chinese HLA-DQAl*0601 homozygous cell SMY-43A, including cis-acting element X, Y,Y2 and W box, was PCR-amplified and sequenced. Our results showed sequence difference of the two nucleotides in site -215 and -216 of W box (as G and C) when compared with the nucleotides of correspondent DQAl*0601 QAP (as A and G) in Caucacian, which implys that the QAP polymorphism of SMY-43A might be unique for Chinese population.
【CateGory Index】: R392
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 HUANG Li-dong, et al. Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025;Analysis of the Chinese HLA-DR5 Subtypes with PCR-RFLP Method[J];Chinese Journal of Immunology;1991-04
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 Huang Lidong Lu Peihua Fu Saili Zhou Guangyan Shanghai Institute of Immunology, Shanghai Sscond Medical University;ANALYSIS OF THE POLYMORPHIC DQ GENES OF CHINESE HLA HOMOZYGOTES WITH PCR-RFLP METHOD[J];;1992-05
2 Fu SL, Chou KY, Lu PH, et al. (Shanghai Institute of Immunology, Shanghai Second Medical University, Shanghai 200025);Genetic Control of Trichosanthin -induced Immunosuppression in Man III. Detection of Cis-and Trans-coinplementations between HLA-DQA1 and DQB1 Alleles[J];Shanghai J.of Immunology;1997-05
3 Huang Lidong, Lin Lin , Gu Xiujun , et al. (Shangai. Insititute of Immunology , Shanghai Second Medical University 200025);Technique of PCR-RFLP applied in HLA-DQA1 genotyping[J];Chinese Journal of Microbiology and Immunology;1996-01
4 SHEN Zhongyi, SHEN Tianwei, ZHANG Qinghua, et al. Shanghai Second Medical University, Shanghai Institute of Immunology, Shanghai 200025, P. R. China;A study on HLA-DP gene crossmatching test with PCR-fingerprinting by introducing a monkey′s DPB-like gene[J];Chinese Journal of Microbiology and Immunology;2001-02
5 LU Pei-hua et al.Shanghai Institute of ImmunologyShanghai Second Medical University,Shanghai 200025,China;Sequence Anal ysis of HLA—DRw 12 Subtypes Found in Chinese Homozygous Cells[J];Chinese Journal of Immunology;1992-06
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